Identifying Cognitive Mechanisms Targeted for Treatment Development in Schizophrenia: An Overview of the First Meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia Initiative

Cameron S Carter, Deanna M. Barch, Robert W. Buchanan, Ed Bullmore, John H. Krystal, Jonathan Cohen, Mark Geyer, Michael Green, Keith H. Nuechterlein, Trevor Robbins, Steven Silverstein, Edward E. Smith, Milton Strauss, Til Wykes, Robert Heinssen

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Abstract

This overview describes the generation and development of the ideas that led to the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative. It also describes the organization, process, and products of the first meeting. The CNTRICS initiative involves a series of three conferences that will systematically address barriers to translating paradigms developed in the basic animal and human cognitive neuroscience fields for use in translational research aimed at developing novel treatments for cognitive impairments in schizophrenia. The articles in this special section report on the results of the first conference, which used a criterion-based consensus-building process to develop a set of cognitive constructs to be targeted for translation efforts.

Original languageEnglish (US)
Pages (from-to)4-10
Number of pages7
JournalBiological Psychiatry
Volume64
Issue number1
DOIs
StatePublished - Jul 1 2008

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Keywords

  • Cognitive neuroscience
  • schizophrenia
  • translational research
  • treatment development

ASJC Scopus subject areas

  • Biological Psychiatry

Cite this

Carter, C. S., Barch, D. M., Buchanan, R. W., Bullmore, E., Krystal, J. H., Cohen, J., Geyer, M., Green, M., Nuechterlein, K. H., Robbins, T., Silverstein, S., Smith, E. E., Strauss, M., Wykes, T., & Heinssen, R. (2008). Identifying Cognitive Mechanisms Targeted for Treatment Development in Schizophrenia: An Overview of the First Meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia Initiative. Biological Psychiatry, 64(1), 4-10. https://doi.org/10.1016/j.biopsych.2008.03.020