Identification of the Serum-Responsive Transcription Initiation Site of the Zinc Finger Gene Krox-20

Janelle Cortner, Peggy J. Farnham

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

The Krox-20 gene is rapidly and transiently induced when quiescent 3T3 cells are stimulated to reenter the proliferative cycle. We identified the major serum-responsive transcription initiation site and found that it differs from the initiation sites previously identified for the Krox-20 gene. Transcripts from the major serum-responsive initiation site increased at least 40-fold in serum-stimulated cells compared with logarithmically growing cells.

Original languageEnglish (US)
Pages (from-to)3788-3791
Number of pages4
JournalMolecular and Cellular Biology
Volume10
Issue number7
StatePublished - Jul 1990
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cell Biology

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