Identification of bluetongue virus-specific immunoglobulin E in cattle.

G. A. Anderson, Jeffrey L Stott, Laurel J Gershwin, Bennie Osburn

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

A modified passive cutaneous anaphylaxis test and an ELISA were used to identify IgE in calves vaccinated (sensitized) with chlorine dioxide-inactivated bluetongue virus (BTV) and in calves inoculated with infectious BTV. The levels of IgE were greatest in the vaccinated calves after challenge with infectious virus, which correlated with development of clinically apparent dermatitis and stomatitis. These findings suggest that some aspects of clinical bluetongue disease in cattle may have an immunopathological mechanism mediated by IgE (type I hypersensitivity).

Original languageEnglish (US)
JournalJournal of General Virology
Volume68
StatePublished - Sep 1987
Externally publishedYes

Fingerprint

Bluetongue virus
Immunoglobulin E
Bluetongue
Cattle Diseases
Immediate Hypersensitivity
Stomatitis
Passive Cutaneous Anaphylaxis
Dermatitis
Skin Tests
Enzyme-Linked Immunosorbent Assay
Viruses

ASJC Scopus subject areas

  • Immunology
  • Virology

Cite this

Identification of bluetongue virus-specific immunoglobulin E in cattle. / Anderson, G. A.; Stott, Jeffrey L; Gershwin, Laurel J; Osburn, Bennie.

In: Journal of General Virology, Vol. 68, 09.1987.

Research output: Contribution to journalArticle

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