Identification of agrinSN isoform and muscle-specific receptor tyrosine kinase in sperm

Priyadarsini Kumar, Michael J Ferns, Stanley Meizel

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

We previously demonstrated several nicotinic acetylcholine receptor (nAChR) subunits and associated proteins in human sperm. Here, we identified in sperm for the first time two additional nAChR-associated molecules: (1) agrin SNZ+ in human sperm localized in the posterior post-acrosomal, neck, and flagellar mid-piece regions; (2) a low-molecular weight isoform of muscle-specific receptor tyrosine kinase in human and mouse sperm localized in the flagellar mid-piece of human sperm.

Original languageEnglish (US)
Pages (from-to)522-528
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume342
Issue number2
DOIs
StatePublished - Apr 7 2006

Keywords

  • Agrin
  • Muscle-specific receptor tyrosine kinase
  • nAChR
  • Sperm

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

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