Identification of agrinSN isoform and muscle-specific receptor tyrosine kinase in sperm

Priyadarsini Kumar, Michael J Ferns, Stanley Meizel

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

We previously demonstrated several nicotinic acetylcholine receptor (nAChR) subunits and associated proteins in human sperm. Here, we identified in sperm for the first time two additional nAChR-associated molecules: (1) agrin SNZ+ in human sperm localized in the posterior post-acrosomal, neck, and flagellar mid-piece regions; (2) a low-molecular weight isoform of muscle-specific receptor tyrosine kinase in human and mouse sperm localized in the flagellar mid-piece of human sperm.

Original languageEnglish (US)
Pages (from-to)522-528
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume342
Issue number2
DOIs
StatePublished - Apr 7 2006

Keywords

  • Agrin
  • Muscle-specific receptor tyrosine kinase
  • nAChR
  • Sperm

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

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