Identification of agrinSN isoform and muscle-specific receptor tyrosine kinase in sperm

Priyadarsini Kumar; Michael J Ferns; Stanley Meizel

doi:10.1016/j.bbrc.2006.01.161

Identification of agrin_SN isoform and muscle-specific receptor tyrosine kinase in sperm

Priyadarsini Kumar, Michael J Ferns, Stanley Meizel

Anesthesiology and Pain Medicine

Research output: Contribution to journal › Article

8 Scopus citations

Abstract

We previously demonstrated several nicotinic acetylcholine receptor (nAChR) subunits and associated proteins in human sperm. Here, we identified in sperm for the first time two additional nAChR-associated molecules: (1) agrin _SNZ⁺ in human sperm localized in the posterior post-acrosomal, neck, and flagellar mid-piece regions; (2) a low-molecular weight isoform of muscle-specific receptor tyrosine kinase in human and mouse sperm localized in the flagellar mid-piece of human sperm.

Original language	English (US)
Pages (from-to)	522-528
Number of pages	7
Journal	Biochemical and Biophysical Research Communications
Volume	342
Issue number	2
DOIs	https://doi.org/10.1016/j.bbrc.2006.01.161
State	Published - Apr 7 2006

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Keywords

Agrin
Muscle-specific receptor tyrosine kinase
nAChR
Sperm

ASJC Scopus subject areas

Biochemistry
Biophysics
Molecular Biology

Cite this

Kumar, P., Ferns, M. J., & Meizel, S. (2006). Identification of agrin_SN isoform and muscle-specific receptor tyrosine kinase in sperm. Biochemical and Biophysical Research Communications, 342(2), 522-528. https://doi.org/10.1016/j.bbrc.2006.01.161

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Access to Document

10.1016/j.bbrc.2006.01.161