Identification of a neutralizing epitope shared by bluetongue virus serotypes 2 and 13.

S. Ristow, L. Leendersten, J. Gorham, Tilahun Yilma

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Abstract

The serotypes of bluetongue virus (BTV) are classified by differences in neutralization commonly induced by P2, a major surface protein. A BTV serotype 13 (BTV-13) monoclonal antibody, 4B13-207A, immunoprecipitated P2s of BTV-13 and BTV-2 and also neutralized both viruses. These data indicate that P2s from BTV-13 and BTV-2 share a common neutralizing epitope that is not detected by neutralizing polyclonal antibody to BTV-13.

Original languageEnglish (US)
Pages (from-to)2502-2504
Number of pages3
JournalJournal of Virology
Volume62
Issue number7
StatePublished - Jul 1988

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ASJC Scopus subject areas

  • Immunology

Cite this

Ristow, S., Leendersten, L., Gorham, J., & Yilma, T. (1988). Identification of a neutralizing epitope shared by bluetongue virus serotypes 2 and 13. Journal of Virology, 62(7), 2502-2504.