Abstract
Infectious bursal disease virus (IBDV) causes an economically important, immunosuppressive disease in chickens. There are two serotypes of the virus that contain a bi-segmented double-stranded RNA genome. In December 2008, the first very virulent (vv)IBDV was identified in California, USA and in 2009 we isolated reassortant viruses in two different locations. Genome segment A of these reassortants was typical of vvIBDV serotype 1 but genome segment B was most similar to IBDV serotype 2. The CA-K785 reassortant caused 20% mortality in chickens but no morbidity or mortality in commercial turkey poults despite being infectious. There have been previous reports of natural reassortants between vvIBDV and other serotype 1 strains, but a natural reassortant between IBDV serotypes 1 and 2 has not been described. The apparent reassorting of California vvIBDV with an endemic serotype 2 virus indicates a common host and suggests vvIBDV may have entered California earlier than originally thought.
Original language | English (US) |
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Pages (from-to) | 98-105 |
Number of pages | 8 |
Journal | Virology |
Volume | 420 |
Issue number | 2 |
DOIs | |
State | Published - Nov 25 2011 |
Keywords
- Birnavirus
- Infectious bursal disease
- Infectious bursal disease virus
- Pathogenicity
- Reassortant
- Serotypes 1 and 2
ASJC Scopus subject areas
- Virology