Identical progression of juvenile hereditary nephronophthisis in monozygotic twins

Sudesh P Makker, Warren E. Grupe, Eugene Perrin, Walter Heymann

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A pair of monozygotic twins with juvenile hereditary nephronophthisis was studiedfor nearly ten years. Astonishing similarity was observed in the clinical course, progression, and histopathology of the disease. In a review of the natural history of various diseases in identical twins it was noted that diseases of infectious or immunologic pathogenesis usually do not follow identical courses. Diseases due to inborn errors of metabolism are more likely to do so. It is suggested that juvenile hereditary nephronophthisis might be due to an inborn error of metabolism.

Original languageEnglish (US)
Pages (from-to)773-779
Number of pages7
JournalThe Journal of Pediatrics
Volume82
Issue number5
DOIs
StatePublished - 1973
Externally publishedYes

Fingerprint

Inborn Errors Metabolism
Monozygotic Twins
Diseases in Twins
Immune System Diseases
Communicable Diseases
Disease Progression
Familial juvenile Nephronophthisis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Identical progression of juvenile hereditary nephronophthisis in monozygotic twins. / Makker, Sudesh P; Grupe, Warren E.; Perrin, Eugene; Heymann, Walter.

In: The Journal of Pediatrics, Vol. 82, No. 5, 1973, p. 773-779.

Research output: Contribution to journalArticle

Makker, Sudesh P ; Grupe, Warren E. ; Perrin, Eugene ; Heymann, Walter. / Identical progression of juvenile hereditary nephronophthisis in monozygotic twins. In: The Journal of Pediatrics. 1973 ; Vol. 82, No. 5. pp. 773-779.
@article{a1986abb2288440f860b4b1fbbb35800,
title = "Identical progression of juvenile hereditary nephronophthisis in monozygotic twins",
abstract = "A pair of monozygotic twins with juvenile hereditary nephronophthisis was studiedfor nearly ten years. Astonishing similarity was observed in the clinical course, progression, and histopathology of the disease. In a review of the natural history of various diseases in identical twins it was noted that diseases of infectious or immunologic pathogenesis usually do not follow identical courses. Diseases due to inborn errors of metabolism are more likely to do so. It is suggested that juvenile hereditary nephronophthisis might be due to an inborn error of metabolism.",
author = "Makker, {Sudesh P} and Grupe, {Warren E.} and Eugene Perrin and Walter Heymann",
year = "1973",
doi = "10.1016/S0022-3476(73)80065-4",
language = "English (US)",
volume = "82",
pages = "773--779",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "5",

}

TY - JOUR

T1 - Identical progression of juvenile hereditary nephronophthisis in monozygotic twins

AU - Makker, Sudesh P

AU - Grupe, Warren E.

AU - Perrin, Eugene

AU - Heymann, Walter

PY - 1973

Y1 - 1973

N2 - A pair of monozygotic twins with juvenile hereditary nephronophthisis was studiedfor nearly ten years. Astonishing similarity was observed in the clinical course, progression, and histopathology of the disease. In a review of the natural history of various diseases in identical twins it was noted that diseases of infectious or immunologic pathogenesis usually do not follow identical courses. Diseases due to inborn errors of metabolism are more likely to do so. It is suggested that juvenile hereditary nephronophthisis might be due to an inborn error of metabolism.

AB - A pair of monozygotic twins with juvenile hereditary nephronophthisis was studiedfor nearly ten years. Astonishing similarity was observed in the clinical course, progression, and histopathology of the disease. In a review of the natural history of various diseases in identical twins it was noted that diseases of infectious or immunologic pathogenesis usually do not follow identical courses. Diseases due to inborn errors of metabolism are more likely to do so. It is suggested that juvenile hereditary nephronophthisis might be due to an inborn error of metabolism.

UR - http://www.scopus.com/inward/record.url?scp=0015618309&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015618309&partnerID=8YFLogxK

U2 - 10.1016/S0022-3476(73)80065-4

DO - 10.1016/S0022-3476(73)80065-4

M3 - Article

VL - 82

SP - 773

EP - 779

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 5

ER -