Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: Report on two deaths in video-EEG-monitored patients

Lisa M. Bateman, Mark Spitz, Masud Seyal

Research output: Contribution to journalArticle

102 Citations (Scopus)

Abstract

Sudden unexplained death in epilepsy (SUDEP) is a common cause of death in patients with epilepsy, with cardiorespiratory dysfunction and a primary cessation of cerebral function proposed as causes. We report two cases of SUDEP in patients with intractable temporal lobe epilepsy undergoing video-EEG (electroencephalography) telemetry at two centers. Both had secondarily generalized convulsions. EEG, electrocardiography (ECG), and respiratory changes in these two patients are reported herein. Ictal/postictal hypoventilation may contribute to SUDEP with the resulting hypoxemia and acidosis leading to failure of recovery of cortical function and eventual cardiac failure.

Original languageEnglish (US)
Pages (from-to)916-920
Number of pages5
JournalEpilepsia
Volume51
Issue number5
DOIs
StatePublished - May 2010

Fingerprint

Hypoventilation
Sudden Death
Cardiac Arrhythmias
Electroencephalography
Epilepsy
Stroke
Telemetry
Temporal Lobe Epilepsy
Recovery of Function
Acidosis
Cause of Death
Electrocardiography
Seizures
Heart Failure

Keywords

  • Epilepsy monitoring unit
  • Hypercapnia
  • Hypoxemia
  • Sudden unexpected death in epilepsy
  • SUDEP

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP : Report on two deaths in video-EEG-monitored patients. / Bateman, Lisa M.; Spitz, Mark; Seyal, Masud.

In: Epilepsia, Vol. 51, No. 5, 05.2010, p. 916-920.

Research output: Contribution to journalArticle

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