Abstract
Sudden unexplained death in epilepsy (SUDEP) is a common cause of death in patients with epilepsy, with cardiorespiratory dysfunction and a primary cessation of cerebral function proposed as causes. We report two cases of SUDEP in patients with intractable temporal lobe epilepsy undergoing video-EEG (electroencephalography) telemetry at two centers. Both had secondarily generalized convulsions. EEG, electrocardiography (ECG), and respiratory changes in these two patients are reported herein. Ictal/postictal hypoventilation may contribute to SUDEP with the resulting hypoxemia and acidosis leading to failure of recovery of cortical function and eventual cardiac failure.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 916-920 |
| Number of pages | 5 |
| Journal | Epilepsia |
| Volume | 51 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 2010 |
Keywords
- Epilepsy monitoring unit
- Hypercapnia
- Hypoxemia
- Sudden unexpected death in epilepsy
- SUDEP
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
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Bateman, L. M., Spitz, M., & Seyal, M. (2010). Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: Report on two deaths in video-EEG-monitored patients. Epilepsia, 51(5), 916-920. https://doi.org/10.1111/j.1528-1167.2009.02513.x