Abstract
Sudden unexplained death in epilepsy (SUDEP) is a common cause of death in patients with epilepsy, with cardiorespiratory dysfunction and a primary cessation of cerebral function proposed as causes. We report two cases of SUDEP in patients with intractable temporal lobe epilepsy undergoing video-EEG (electroencephalography) telemetry at two centers. Both had secondarily generalized convulsions. EEG, electrocardiography (ECG), and respiratory changes in these two patients are reported herein. Ictal/postictal hypoventilation may contribute to SUDEP with the resulting hypoxemia and acidosis leading to failure of recovery of cortical function and eventual cardiac failure.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 916-920 |
| Number of pages | 5 |
| Journal | Epilepsia |
| Volume | 51 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 2010 |
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Keywords
- Epilepsy monitoring unit
- Hypercapnia
- Hypoxemia
- Sudden unexpected death in epilepsy
- SUDEP
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
Cite this
Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP : Report on two deaths in video-EEG-monitored patients. / Bateman, Lisa M.; Spitz, Mark; Seyal, Masud.
In: Epilepsia, Vol. 51, No. 5, 05.2010, p. 916-920.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP
T2 - Report on two deaths in video-EEG-monitored patients
AU - Bateman, Lisa M.
AU - Spitz, Mark
AU - Seyal, Masud
PY - 2010/5
Y1 - 2010/5
N2 - Sudden unexplained death in epilepsy (SUDEP) is a common cause of death in patients with epilepsy, with cardiorespiratory dysfunction and a primary cessation of cerebral function proposed as causes. We report two cases of SUDEP in patients with intractable temporal lobe epilepsy undergoing video-EEG (electroencephalography) telemetry at two centers. Both had secondarily generalized convulsions. EEG, electrocardiography (ECG), and respiratory changes in these two patients are reported herein. Ictal/postictal hypoventilation may contribute to SUDEP with the resulting hypoxemia and acidosis leading to failure of recovery of cortical function and eventual cardiac failure.
AB - Sudden unexplained death in epilepsy (SUDEP) is a common cause of death in patients with epilepsy, with cardiorespiratory dysfunction and a primary cessation of cerebral function proposed as causes. We report two cases of SUDEP in patients with intractable temporal lobe epilepsy undergoing video-EEG (electroencephalography) telemetry at two centers. Both had secondarily generalized convulsions. EEG, electrocardiography (ECG), and respiratory changes in these two patients are reported herein. Ictal/postictal hypoventilation may contribute to SUDEP with the resulting hypoxemia and acidosis leading to failure of recovery of cortical function and eventual cardiac failure.
KW - Epilepsy monitoring unit
KW - Hypercapnia
KW - Hypoxemia
KW - Sudden unexpected death in epilepsy
KW - SUDEP
UR - http://www.scopus.com/inward/record.url?scp=77951539335&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951539335&partnerID=8YFLogxK
U2 - 10.1111/j.1528-1167.2009.02513.x
DO - 10.1111/j.1528-1167.2009.02513.x
M3 - Article
C2 - 20132291
AN - SCOPUS:77951539335
VL - 51
SP - 916
EP - 920
JO - Epilepsia
JF - Epilepsia
SN - 0013-9580
IS - 5
ER -