Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: Report on two deaths in video-EEG-monitored patients

Lisa M. Bateman; Mark Spitz; Masud Seyal

doi:10.1111/j.1528-1167.2009.02513.x

Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: Report on two deaths in video-EEG-monitored patients

Lisa M. Bateman, Mark Spitz, Masud Seyal

Neurology

Research output: Contribution to journal › Article › peer-review

112 Scopus citations

Abstract

Sudden unexplained death in epilepsy (SUDEP) is a common cause of death in patients with epilepsy, with cardiorespiratory dysfunction and a primary cessation of cerebral function proposed as causes. We report two cases of SUDEP in patients with intractable temporal lobe epilepsy undergoing video-EEG (electroencephalography) telemetry at two centers. Both had secondarily generalized convulsions. EEG, electrocardiography (ECG), and respiratory changes in these two patients are reported herein. Ictal/postictal hypoventilation may contribute to SUDEP with the resulting hypoxemia and acidosis leading to failure of recovery of cortical function and eventual cardiac failure.

Original language	English (US)
Pages (from-to)	916-920
Number of pages	5
Journal	Epilepsia
Volume	51
Issue number	5
DOIs	https://doi.org/10.1111/j.1528-1167.2009.02513.x
State	Published - May 2010

Keywords

Epilepsy monitoring unit
Hypercapnia
Hypoxemia
Sudden unexpected death in epilepsy
SUDEP

ASJC Scopus subject areas

Clinical Neurology
Neurology

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Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: Report on two deaths in video-EEG-monitored patients

Abstract

Keywords

ASJC Scopus subject areas

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