Ibex-Associated Malignant Catarrhal Fever-Like Disease in a Group of Bongo Antelope (Tragelaphus eurycerus)

D. Gasper, B. Barr, H. Li, N. Taus, R. Peterson, G. Benjamin, T. Hunt, Patricia Pesavento

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A private zoological facility experienced an outbreak of malignant catarrhal fever (MCF) in 3 bongo antelope (Tragelaphus eurycerus). All cases were periparturient bongos that presented acutely anorectic beginning ~6 weeks after being housed with a Nubian ibex. Disease quickly progressed to respiratory distress and death within 24-72 hours of onset of clinical signs. Consistent gross findings in affected bongos were pulmonary edema and small pale tan foci in the livers. Histological lesions included a nonsuppurative vasculitis in multiple tissues, which is well recognized in MCF, but additionally included necrotizing cholangiohepatitis and neutrophilic, necrotizing myocarditis. Ibex-associated viral DNA was detected by polymerase chain reaction and was identical in sequence whether derived from bongos or ibex. The sequence closely matched an MCF viral DNA fragment that had been amplified from an ibex and bongo in a previous case report.

Original languageEnglish (US)
Pages (from-to)492-497
Number of pages6
JournalVeterinary Pathology
Volume49
Issue number3
DOIs
StatePublished - May 2012

Fingerprint

Malignant Catarrh
Antelopes
Tragelaphus
malignant catarrhal fever
Capra
antelopes
Viral DNA
Appetite Depressants
Myocarditis
Pulmonary Edema
Vasculitis
vasculitis
myocarditis
Disease Outbreaks
DNA
distress
lesions (animal)
edema
Polymerase Chain Reaction
Liver

Keywords

  • bongo antelope
  • histopathology
  • malignant catarrhal fever
  • MCFV-ibex
  • Nubian ibex
  • polymerase chain reaction
  • sequencing

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Ibex-Associated Malignant Catarrhal Fever-Like Disease in a Group of Bongo Antelope (Tragelaphus eurycerus). / Gasper, D.; Barr, B.; Li, H.; Taus, N.; Peterson, R.; Benjamin, G.; Hunt, T.; Pesavento, Patricia.

In: Veterinary Pathology, Vol. 49, No. 3, 05.2012, p. 492-497.

Research output: Contribution to journalArticle

Gasper, D. ; Barr, B. ; Li, H. ; Taus, N. ; Peterson, R. ; Benjamin, G. ; Hunt, T. ; Pesavento, Patricia. / Ibex-Associated Malignant Catarrhal Fever-Like Disease in a Group of Bongo Antelope (Tragelaphus eurycerus). In: Veterinary Pathology. 2012 ; Vol. 49, No. 3. pp. 492-497.
@article{5e5c740ee17f4996868123e3557814c0,
title = "Ibex-Associated Malignant Catarrhal Fever-Like Disease in a Group of Bongo Antelope (Tragelaphus eurycerus)",
abstract = "A private zoological facility experienced an outbreak of malignant catarrhal fever (MCF) in 3 bongo antelope (Tragelaphus eurycerus). All cases were periparturient bongos that presented acutely anorectic beginning ~6 weeks after being housed with a Nubian ibex. Disease quickly progressed to respiratory distress and death within 24-72 hours of onset of clinical signs. Consistent gross findings in affected bongos were pulmonary edema and small pale tan foci in the livers. Histological lesions included a nonsuppurative vasculitis in multiple tissues, which is well recognized in MCF, but additionally included necrotizing cholangiohepatitis and neutrophilic, necrotizing myocarditis. Ibex-associated viral DNA was detected by polymerase chain reaction and was identical in sequence whether derived from bongos or ibex. The sequence closely matched an MCF viral DNA fragment that had been amplified from an ibex and bongo in a previous case report.",
keywords = "bongo antelope, histopathology, malignant catarrhal fever, MCFV-ibex, Nubian ibex, polymerase chain reaction, sequencing",
author = "D. Gasper and B. Barr and H. Li and N. Taus and R. Peterson and G. Benjamin and T. Hunt and Patricia Pesavento",
year = "2012",
month = "5",
doi = "10.1177/0300985811429306",
language = "English (US)",
volume = "49",
pages = "492--497",
journal = "Veterinary Pathology",
issn = "0300-9858",
publisher = "SAGE Publications Ltd",
number = "3",

}

TY - JOUR

T1 - Ibex-Associated Malignant Catarrhal Fever-Like Disease in a Group of Bongo Antelope (Tragelaphus eurycerus)

AU - Gasper, D.

AU - Barr, B.

AU - Li, H.

AU - Taus, N.

AU - Peterson, R.

AU - Benjamin, G.

AU - Hunt, T.

AU - Pesavento, Patricia

PY - 2012/5

Y1 - 2012/5

N2 - A private zoological facility experienced an outbreak of malignant catarrhal fever (MCF) in 3 bongo antelope (Tragelaphus eurycerus). All cases were periparturient bongos that presented acutely anorectic beginning ~6 weeks after being housed with a Nubian ibex. Disease quickly progressed to respiratory distress and death within 24-72 hours of onset of clinical signs. Consistent gross findings in affected bongos were pulmonary edema and small pale tan foci in the livers. Histological lesions included a nonsuppurative vasculitis in multiple tissues, which is well recognized in MCF, but additionally included necrotizing cholangiohepatitis and neutrophilic, necrotizing myocarditis. Ibex-associated viral DNA was detected by polymerase chain reaction and was identical in sequence whether derived from bongos or ibex. The sequence closely matched an MCF viral DNA fragment that had been amplified from an ibex and bongo in a previous case report.

AB - A private zoological facility experienced an outbreak of malignant catarrhal fever (MCF) in 3 bongo antelope (Tragelaphus eurycerus). All cases were periparturient bongos that presented acutely anorectic beginning ~6 weeks after being housed with a Nubian ibex. Disease quickly progressed to respiratory distress and death within 24-72 hours of onset of clinical signs. Consistent gross findings in affected bongos were pulmonary edema and small pale tan foci in the livers. Histological lesions included a nonsuppurative vasculitis in multiple tissues, which is well recognized in MCF, but additionally included necrotizing cholangiohepatitis and neutrophilic, necrotizing myocarditis. Ibex-associated viral DNA was detected by polymerase chain reaction and was identical in sequence whether derived from bongos or ibex. The sequence closely matched an MCF viral DNA fragment that had been amplified from an ibex and bongo in a previous case report.

KW - bongo antelope

KW - histopathology

KW - malignant catarrhal fever

KW - MCFV-ibex

KW - Nubian ibex

KW - polymerase chain reaction

KW - sequencing

UR - http://www.scopus.com/inward/record.url?scp=84860471087&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84860471087&partnerID=8YFLogxK

U2 - 10.1177/0300985811429306

DO - 10.1177/0300985811429306

M3 - Article

VL - 49

SP - 492

EP - 497

JO - Veterinary Pathology

JF - Veterinary Pathology

SN - 0300-9858

IS - 3

ER -