TY - JOUR
T1 - Ibex-Associated Malignant Catarrhal Fever in Duikers (Cephalophus Spp)
AU - Carvallo, Francisco R.
AU - Uzal, Francisco A.
AU - Moore, Janet D.
AU - Jackson, Kenneth
AU - Nyaoke, Akinyi C.
AU - Naples, Lisa
AU - Davis-Powell, Jordan
AU - Stadler, Cynthia K.
AU - Boren, Brandon A.
AU - Cunha, Cristina
AU - Li, Hong
AU - Pesavento, Patricia A.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Eight duikers, representing 3 different species cohoused in a single zoological collection, died in a 10-month period. Black, red-flanked, and yellow-backed duikers were affected, appearing clinically with a combination of anorexia, diarrhea, ataxia, tremors, and/or stupor, followed by death within 72 hours of onset of clinical signs. Consistent gross findings were pulmonary ecchymoses (8/8), generalized lymphadenomegaly (6/8), ascites (5/8), and pleural effusion (4/8). Dense lymphocyte infiltrates and arteritis affected numerous tissues in most animals. Ibex-associated malignant catarrhal fever (MCF) viral DNA was detected in all cases by polymerase chain reaction and in situ hybridization. Identical ibex-MCF virus sequence was detected in spleen of a clinically healthy ibex (Capra ibex) housed in a separate enclosure 35 meters away from the duikers.
AB - Eight duikers, representing 3 different species cohoused in a single zoological collection, died in a 10-month period. Black, red-flanked, and yellow-backed duikers were affected, appearing clinically with a combination of anorexia, diarrhea, ataxia, tremors, and/or stupor, followed by death within 72 hours of onset of clinical signs. Consistent gross findings were pulmonary ecchymoses (8/8), generalized lymphadenomegaly (6/8), ascites (5/8), and pleural effusion (4/8). Dense lymphocyte infiltrates and arteritis affected numerous tissues in most animals. Ibex-associated malignant catarrhal fever (MCF) viral DNA was detected in all cases by polymerase chain reaction and in situ hybridization. Identical ibex-MCF virus sequence was detected in spleen of a clinically healthy ibex (Capra ibex) housed in a separate enclosure 35 meters away from the duikers.
KW - cephalophinae
KW - duiker
KW - gammaherpesvirus
KW - Ibex
KW - Ibex-MCFV
KW - in situ hybridization
KW - malignant catarrhal fever
KW - virus
UR - http://www.scopus.com/inward/record.url?scp=85084812814&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85084812814&partnerID=8YFLogxK
U2 - 10.1177/0300985820918313
DO - 10.1177/0300985820918313
M3 - Article
C2 - 32406327
AN - SCOPUS:85084812814
JO - Pathologia veterinaria
JF - Pathologia veterinaria
SN - 0300-9858
ER -