Hypothesis: The protein body effect and other aspects of food matrix effects

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

With regard to the allergenicity of edible seeds and nuts, certain proteins may not be immediately accessible to digestion in the stomach and the upper small intestine because of the nature of the organization of such proteins into protein body organelles. Protein body hydration status, interactions between proteins, phytochemicals, protease inhibitors, and other matrix effects may contribute to the ability of a protein or package of proteins to reach the sites of active immune sampling in the gastrointestinal mucosa and thus be an influence on the potential allergenicity of a protein.

Original languageEnglish (US)
Pages (from-to)111-116
Number of pages6
JournalAnnals of the New York Academy of Sciences
Volume964
StatePublished - 2002

Fingerprint

Food
Proteins
Nuts
Protein
Phytochemicals
Protease Inhibitors
Hydration
Organelles
Small Intestine
Seed
Digestion
Catalytic Domain
Seeds
Stomach
Mucous Membrane
Sampling

Keywords

  • Food allergy
  • Food matrix effects
  • Protein body effect

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

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abstract = "With regard to the allergenicity of edible seeds and nuts, certain proteins may not be immediately accessible to digestion in the stomach and the upper small intestine because of the nature of the organization of such proteins into protein body organelles. Protein body hydration status, interactions between proteins, phytochemicals, protease inhibitors, and other matrix effects may contribute to the ability of a protein or package of proteins to reach the sites of active immune sampling in the gastrointestinal mucosa and thus be an influence on the potential allergenicity of a protein.",
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