Hyperparathyroidism of Renal Disease

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Renal hyperparathyroidism (rHPT) is a common complication of chronic kidney disease characterized by elevated parathyroid hormone levels secondary to derangements in the homeostasis of calcium, phosphate, and vitamin D. Patients with rHPT experience increased rates of cardiovascular problems and bone disease. The Kidney Disease: Improving Global Outcomes guidelines recommend that screening and management of rHPT be initiated for all patients with chronic kidney disease stage 3 (estimated glomerular filtration rate, < 60 mL/min/1.73 m(2)). Since the 1990s, improving medical management with vitamin D analogs, phosphate binders, and calcimimetic drugs has expanded the treatment options for patients with rHPT, but some patients still require a parathyroidectomy to mitigate the sequelae of this challenging disease.

Original languageEnglish (US)
Pages (from-to)78-83
Number of pages6
JournalThe Permanente journal
Volume20
Issue number3
DOIs
StatePublished - Jun 1 2016

ASJC Scopus subject areas

  • Medicine(all)

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