Hyperleukocytosis in a premature infant with intrauterine herpes simplex encephalitis

Mark Underwood, A. E. Wartell, R. A. Borghese

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Herpes encephalitis is a rare but devastating infection in premature infants. We report a 29 week gestation infant with severe intrauterine cutaneous and central nervous system herpes accompanied by hyperleukocytosis. Leukemoid reactions are not uncommon in this population, but the association of herpes encephalitis and a leukemoid reaction or hyperleukocytosis has not been reported previously.

Original languageEnglish (US)
Pages (from-to)469-472
Number of pages4
JournalJournal of Perinatology
Issue number6
StatePublished - Jun 2012


  • encephalitis
  • herpes
  • leukemoid reaction
  • leukocytosis
  • premature infant

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health


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