Hydrochlorothiazide reduces urinary calcium excretion in a child with Lowe syndrome

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

There is a growing recognition that children with Lowe syndrome are at risk of nephrocalcinosis and nephrolithiasis from hypercalciuria. Increased fluid intake and correction of metabolic acidosis have remained the focus for intervention but are not always successful. Thiazide diuretics, which reduce urinary calcium excretion, have not been used in these children, due to concerns that (i) they may not work as a result of the underlying tubular abnormalities and (ii) their risk may outweigh the potential benefits they have to offer. Herein we report a child with Lowe syndrome whowas successfully treated with thiazides in managing his hypercalciuria.

Original languageEnglish (US)
Pages (from-to)459-461
Number of pages3
JournalClinical Kidney Journal
Volume8
Issue number4
DOIs
StatePublished - 2015

Fingerprint

Oculocerebrorenal Syndrome
Hydrochlorothiazide
Hypercalciuria
Calcium
Nephrocalcinosis
Thiazides
Sodium Chloride Symporter Inhibitors
Nephrolithiasis
Acidosis

Keywords

  • Nephrolithiasis
  • Thiazides
  • Tubulopathy
  • Urinary calcium excretion

ASJC Scopus subject areas

  • Nephrology
  • Transplantation

Cite this

Hydrochlorothiazide reduces urinary calcium excretion in a child with Lowe syndrome. / Butani, Lavjay.

In: Clinical Kidney Journal, Vol. 8, No. 4, 2015, p. 459-461.

Research output: Contribution to journalArticle

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