Abstract
Hybridization of nucleic acids is a reversible process by which single-stranded nucleic acids are allowed to interact in a sequence-specific manner to form complexes or hybrids. Assays which are based on nucleic acid hybridization are widely utilized in the research and clinical laboratory settings in order to detect and/or quantify specific nucleic acid sequences within samples or specimens.
| Original language | English (US) |
|---|---|
| Title of host publication | Brenner's Encyclopedia of Genetics |
| Subtitle of host publication | Second Edition |
| Publisher | Elsevier Inc. |
| Pages | 593 |
| Number of pages | 1 |
| ISBN (Electronic) | 9780080961569 |
| ISBN (Print) | 9780123749840 |
| DOIs | |
| State | Published - Feb 27 2013 |
| Externally published | Yes |
Keywords
- Complementary base pairing
- FISH
- Hybrid capture
- Nucleic acids
- Probe
- Sequence specificity
- Target
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Medicine(all)
Fingerprint Dive into the research topics of 'Hybridization'. Together they form a unique fingerprint.
Cite this
Barcia, S. M., & Jen, K-Y. (2013). Hybridization. In Brenner's Encyclopedia of Genetics: Second Edition (pp. 593). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-374984-0.00758-0