Abstract
Hybridization of nucleic acids is a reversible process by which single-stranded nucleic acids are allowed to interact in a sequence-specific manner to form complexes or hybrids. Assays which are based on nucleic acid hybridization are widely utilized in the research and clinical laboratory settings in order to detect and/or quantify specific nucleic acid sequences within samples or specimens.
Original language | English (US) |
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Title of host publication | Brenner's Encyclopedia of Genetics |
Subtitle of host publication | Second Edition |
Publisher | Elsevier Inc. |
Pages | 593 |
Number of pages | 1 |
ISBN (Electronic) | 9780080961569 |
ISBN (Print) | 9780123749840 |
DOIs | |
State | Published - Feb 27 2013 |
Externally published | Yes |
Keywords
- Complementary base pairing
- FISH
- Hybrid capture
- Nucleic acids
- Probe
- Sequence specificity
- Target
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Medicine(all)