Hybridization

S. M. Barcia; Kuang-Yu Jen

doi:10.1016/B978-0-12-374984-0.00758-0

Hybridization

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Hybridization of nucleic acids is a reversible process by which single-stranded nucleic acids are allowed to interact in a sequence-specific manner to form complexes or hybrids. Assays which are based on nucleic acid hybridization are widely utilized in the research and clinical laboratory settings in order to detect and/or quantify specific nucleic acid sequences within samples or specimens.

Original language	English (US)
Title of host publication	Brenner's Encyclopedia of Genetics
Subtitle of host publication	Second Edition
Publisher	Elsevier Inc.
Pages	593
Number of pages	1
ISBN (Electronic)	9780080961569
ISBN (Print)	9780123749840
DOIs	https://doi.org/10.1016/B978-0-12-374984-0.00758-0
State	Published - Feb 27 2013
Externally published	Yes

Keywords

Complementary base pairing
FISH
Hybrid capture
Nucleic acids
Probe
Sequence specificity
Target

ASJC Scopus subject areas

Agricultural and Biological Sciences(all)
Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)

Access to Document

10.1016/B978-0-12-374984-0.00758-0

Cite this

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title = "Hybridization",

abstract = "Hybridization of nucleic acids is a reversible process by which single-stranded nucleic acids are allowed to interact in a sequence-specific manner to form complexes or hybrids. Assays which are based on nucleic acid hybridization are widely utilized in the research and clinical laboratory settings in order to detect and/or quantify specific nucleic acid sequences within samples or specimens.",

keywords = "Complementary base pairing, FISH, Hybrid capture, Nucleic acids, Probe, Sequence specificity, Target",

author = "Barcia, {S. M.} and Kuang-Yu Jen",

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AU - Barcia, S. M.

AU - Jen, Kuang-Yu

PY - 2013/2/27

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N2 - Hybridization of nucleic acids is a reversible process by which single-stranded nucleic acids are allowed to interact in a sequence-specific manner to form complexes or hybrids. Assays which are based on nucleic acid hybridization are widely utilized in the research and clinical laboratory settings in order to detect and/or quantify specific nucleic acid sequences within samples or specimens.

AB - Hybridization of nucleic acids is a reversible process by which single-stranded nucleic acids are allowed to interact in a sequence-specific manner to form complexes or hybrids. Assays which are based on nucleic acid hybridization are widely utilized in the research and clinical laboratory settings in order to detect and/or quantify specific nucleic acid sequences within samples or specimens.

KW - Complementary base pairing

KW - FISH

KW - Hybrid capture

KW - Nucleic acids

KW - Probe

KW - Sequence specificity

KW - Target

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DO - 10.1016/B978-0-12-374984-0.00758-0

M3 - Chapter

AN - SCOPUS:85043264099

SN - 9780123749840

SP - 593

BT - Brenner's Encyclopedia of Genetics

PB - Elsevier Inc.

ER -

Hybridization

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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