Humoral recognition of lipopolysaccharide core antigens of gram-negative bacteria in neonatal swine.

J. W. Tyler, James S Cullor, Mark Thurmond, D. W. Hird, K. M. Parker

Research output: Contribution to journalArticle

8 Scopus citations


Serologic recognition of common lipopolysaccharide core antigens has been related to enhanced resistance to gram-negative bacterial disease in several species. Class-specific titers (IgG, IgM) were determined by direct ELISA, using intact Escherichia coli (J5) as a plate antigen. Serum samples were obtained from 224 neonatal swine between the ages of 36 and 60 hours. The mean (+/- SEM) log10 IgG titer against gram-negative core antigens was 1:1,713 +/- 0.4718 and the mean log10 IgM titer was 1:202 +/- 0.5644. The IgG titer was directly related with litter size, birth weight, and serum total IgG concentration; IgM titer was directly related with dam parity and serum total IgG concentration.

Original languageEnglish (US)
Pages (from-to)126-130
Number of pages5
JournalAmerican Journal of Veterinary Research
Issue number1
StatePublished - Jan 1989


ASJC Scopus subject areas

  • veterinary(all)

Cite this