Human natriuretic factor in cirrhotic patients undergoing orthotopic liver transplantation

Pasquale Piccinni, Lorenzo Rossaro, Agnese Graziotto, Antonio Tripepi, Leonardo Meneghetti, Paolo Inturri, Patrizia Burra, Thrinadha Polamarasetti Rao, Mario Plebani, Diego Faggian

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We measured the plasma levels of atrial natriuretic factor (ANF) during orthotopic liver transplantation (OLT) in eight adult patients with cirrhosis and ascites. The aim of this study was to determine whether significant differences in ANF concentration may be detected during the individual phases of OLT and to correlate these changes with hemodynamics. In each patient a hemodynamic assessment was achieved using a Swan-Ganz fiber optic catheter for continuous monitoring of cardiac output (CO), systemic vascular resistance index (SVRI), right filling pressure as assessed by central venous pressure (CVP), and left filling pressure by means of pulmonary arterial wedge pressure (PAWP). During reperfusion a clear-cut increase in ANF values was observed (P<0.05). Concurrently, an increase in CVP (P<0.05) and a decrease in SVRI were observed without any significant increase in diuresis. These data suggest that ANF might play a role in the development of the reperfusion syndrome.

Original languageEnglish (US)
Pages (from-to)51-54
Number of pages4
JournalTransplant International
Volume8
Issue number1
DOIs
StatePublished - Jan 1995
Externally publishedYes

Fingerprint

Natriuretic Agents
Atrial Natriuretic Factor
Liver Transplantation
Central Venous Pressure
Vascular Resistance
Reperfusion
Hemodynamics
Pressure
Pulmonary Wedge Pressure
Diuresis
Ascites
Cardiac Output
Arterial Pressure
Fibrosis
Catheters

Keywords

  • Atrial natriuretic factor, liver transplantation
  • Liver transplantation, atrial natriuretic factor

ASJC Scopus subject areas

  • Transplantation

Cite this

Piccinni, P., Rossaro, L., Graziotto, A., Tripepi, A., Meneghetti, L., Inturri, P., ... Faggian, D. (1995). Human natriuretic factor in cirrhotic patients undergoing orthotopic liver transplantation. Transplant International, 8(1), 51-54. https://doi.org/10.1007/BF00366711

Human natriuretic factor in cirrhotic patients undergoing orthotopic liver transplantation. / Piccinni, Pasquale; Rossaro, Lorenzo; Graziotto, Agnese; Tripepi, Antonio; Meneghetti, Leonardo; Inturri, Paolo; Burra, Patrizia; Rao, Thrinadha Polamarasetti; Plebani, Mario; Faggian, Diego.

In: Transplant International, Vol. 8, No. 1, 01.1995, p. 51-54.

Research output: Contribution to journalArticle

Piccinni, P, Rossaro, L, Graziotto, A, Tripepi, A, Meneghetti, L, Inturri, P, Burra, P, Rao, TP, Plebani, M & Faggian, D 1995, 'Human natriuretic factor in cirrhotic patients undergoing orthotopic liver transplantation', Transplant International, vol. 8, no. 1, pp. 51-54. https://doi.org/10.1007/BF00366711
Piccinni, Pasquale ; Rossaro, Lorenzo ; Graziotto, Agnese ; Tripepi, Antonio ; Meneghetti, Leonardo ; Inturri, Paolo ; Burra, Patrizia ; Rao, Thrinadha Polamarasetti ; Plebani, Mario ; Faggian, Diego. / Human natriuretic factor in cirrhotic patients undergoing orthotopic liver transplantation. In: Transplant International. 1995 ; Vol. 8, No. 1. pp. 51-54.
@article{ee784f12491a4332ad289b80c6d68f5f,
title = "Human natriuretic factor in cirrhotic patients undergoing orthotopic liver transplantation",
abstract = "We measured the plasma levels of atrial natriuretic factor (ANF) during orthotopic liver transplantation (OLT) in eight adult patients with cirrhosis and ascites. The aim of this study was to determine whether significant differences in ANF concentration may be detected during the individual phases of OLT and to correlate these changes with hemodynamics. In each patient a hemodynamic assessment was achieved using a Swan-Ganz fiber optic catheter for continuous monitoring of cardiac output (CO), systemic vascular resistance index (SVRI), right filling pressure as assessed by central venous pressure (CVP), and left filling pressure by means of pulmonary arterial wedge pressure (PAWP). During reperfusion a clear-cut increase in ANF values was observed (P<0.05). Concurrently, an increase in CVP (P<0.05) and a decrease in SVRI were observed without any significant increase in diuresis. These data suggest that ANF might play a role in the development of the reperfusion syndrome.",
keywords = "Atrial natriuretic factor, liver transplantation, Liver transplantation, atrial natriuretic factor",
author = "Pasquale Piccinni and Lorenzo Rossaro and Agnese Graziotto and Antonio Tripepi and Leonardo Meneghetti and Paolo Inturri and Patrizia Burra and Rao, {Thrinadha Polamarasetti} and Mario Plebani and Diego Faggian",
year = "1995",
month = "1",
doi = "10.1007/BF00366711",
language = "English (US)",
volume = "8",
pages = "51--54",
journal = "Transplant International",
issn = "0934-0874",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Human natriuretic factor in cirrhotic patients undergoing orthotopic liver transplantation

AU - Piccinni, Pasquale

AU - Rossaro, Lorenzo

AU - Graziotto, Agnese

AU - Tripepi, Antonio

AU - Meneghetti, Leonardo

AU - Inturri, Paolo

AU - Burra, Patrizia

AU - Rao, Thrinadha Polamarasetti

AU - Plebani, Mario

AU - Faggian, Diego

PY - 1995/1

Y1 - 1995/1

N2 - We measured the plasma levels of atrial natriuretic factor (ANF) during orthotopic liver transplantation (OLT) in eight adult patients with cirrhosis and ascites. The aim of this study was to determine whether significant differences in ANF concentration may be detected during the individual phases of OLT and to correlate these changes with hemodynamics. In each patient a hemodynamic assessment was achieved using a Swan-Ganz fiber optic catheter for continuous monitoring of cardiac output (CO), systemic vascular resistance index (SVRI), right filling pressure as assessed by central venous pressure (CVP), and left filling pressure by means of pulmonary arterial wedge pressure (PAWP). During reperfusion a clear-cut increase in ANF values was observed (P<0.05). Concurrently, an increase in CVP (P<0.05) and a decrease in SVRI were observed without any significant increase in diuresis. These data suggest that ANF might play a role in the development of the reperfusion syndrome.

AB - We measured the plasma levels of atrial natriuretic factor (ANF) during orthotopic liver transplantation (OLT) in eight adult patients with cirrhosis and ascites. The aim of this study was to determine whether significant differences in ANF concentration may be detected during the individual phases of OLT and to correlate these changes with hemodynamics. In each patient a hemodynamic assessment was achieved using a Swan-Ganz fiber optic catheter for continuous monitoring of cardiac output (CO), systemic vascular resistance index (SVRI), right filling pressure as assessed by central venous pressure (CVP), and left filling pressure by means of pulmonary arterial wedge pressure (PAWP). During reperfusion a clear-cut increase in ANF values was observed (P<0.05). Concurrently, an increase in CVP (P<0.05) and a decrease in SVRI were observed without any significant increase in diuresis. These data suggest that ANF might play a role in the development of the reperfusion syndrome.

KW - Atrial natriuretic factor, liver transplantation

KW - Liver transplantation, atrial natriuretic factor

UR - http://www.scopus.com/inward/record.url?scp=0028954373&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028954373&partnerID=8YFLogxK

U2 - 10.1007/BF00366711

DO - 10.1007/BF00366711

M3 - Article

C2 - 7888052

AN - SCOPUS:0028954373

VL - 8

SP - 51

EP - 54

JO - Transplant International

JF - Transplant International

SN - 0934-0874

IS - 1

ER -