Abstract
Computational electrophysiology has proven useful to investigate the mechanisms of cardiac arrhythmias at various spatial scales, from isolated myocytes to the whole heart. This article reviews how mathematical modeling has aided our understanding of human atrial myocyte electrophysiology to study the contribution of structural and electrical remodeling to human atrial fibrillation. Potential new avenues of investigation and model development are suggested.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 145-150 |
| Number of pages | 6 |
| Journal | Trends in Cardiovascular Medicine |
| Volume | 21 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jul 2011 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Human Atrial Fibrillation : Insights From Computational Electrophysiological Models. / Bers, Donald M; Grandi, Eleonora.
In: Trends in Cardiovascular Medicine, Vol. 21, No. 5, 07.2011, p. 145-150.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Human Atrial Fibrillation
T2 - Insights From Computational Electrophysiological Models
AU - Bers, Donald M
AU - Grandi, Eleonora
PY - 2011/7
Y1 - 2011/7
N2 - Computational electrophysiology has proven useful to investigate the mechanisms of cardiac arrhythmias at various spatial scales, from isolated myocytes to the whole heart. This article reviews how mathematical modeling has aided our understanding of human atrial myocyte electrophysiology to study the contribution of structural and electrical remodeling to human atrial fibrillation. Potential new avenues of investigation and model development are suggested.
AB - Computational electrophysiology has proven useful to investigate the mechanisms of cardiac arrhythmias at various spatial scales, from isolated myocytes to the whole heart. This article reviews how mathematical modeling has aided our understanding of human atrial myocyte electrophysiology to study the contribution of structural and electrical remodeling to human atrial fibrillation. Potential new avenues of investigation and model development are suggested.
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UR - http://www.scopus.com/inward/citedby.url?scp=84862736456&partnerID=8YFLogxK
U2 - 10.1016/j.tcm.2012.04.004
DO - 10.1016/j.tcm.2012.04.004
M3 - Article
VL - 21
SP - 145
EP - 150
JO - Trends in Cardiovascular Medicine
JF - Trends in Cardiovascular Medicine
SN - 1050-1738
IS - 5
ER -