Human Atrial Fibrillation

Insights From Computational Electrophysiological Models

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Computational electrophysiology has proven useful to investigate the mechanisms of cardiac arrhythmias at various spatial scales, from isolated myocytes to the whole heart. This article reviews how mathematical modeling has aided our understanding of human atrial myocyte electrophysiology to study the contribution of structural and electrical remodeling to human atrial fibrillation. Potential new avenues of investigation and model development are suggested.

Original languageEnglish (US)
Pages (from-to)145-150
Number of pages6
JournalTrends in Cardiovascular Medicine
Volume21
Issue number5
DOIs
StatePublished - Jul 2011

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Electrophysiology
Atrial Fibrillation
Muscle Cells
Atrial Remodeling
Cardiac Arrhythmias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Human Atrial Fibrillation: Insights From Computational Electrophysiological Models",
abstract = "Computational electrophysiology has proven useful to investigate the mechanisms of cardiac arrhythmias at various spatial scales, from isolated myocytes to the whole heart. This article reviews how mathematical modeling has aided our understanding of human atrial myocyte electrophysiology to study the contribution of structural and electrical remodeling to human atrial fibrillation. Potential new avenues of investigation and model development are suggested.",
author = "Bers, {Donald M} and Eleonora Grandi",
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