The objective was to determine the probability of receiving steroid treatment following an insulin tolerance test (ITT) for short-stature evaluation and to evaluate the utility of a subsequent cortrosyn stimulation test (CST) in determining adrenal sufficiency. We retrospectively analyzed the hypothalamic-pituitary-adrenal (HPA) axis evaluation in short-stature subjects during the 5-year period from January 2005 to December 2009. The probability of receiving steroid treatment was < 10 % when the maximum cortisol concentration during an ITT was < 8.4 μg/dL. In the event of a suboptimal cortisol response during an ITT, only a single 1-μ g CST is recommended for assessment of adrenal function.
- Adrenal deficiency
- Adrenal sufficiency
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Pediatrics, Perinatology, and Child Health