Abstract
The objective was to determine the probability of receiving steroid treatment following an insulin tolerance test (ITT) for short-stature evaluation and to evaluate the utility of a subsequent cortrosyn stimulation test (CST) in determining adrenal sufficiency. We retrospectively analyzed the hypothalamic-pituitary-adrenal (HPA) axis evaluation in short-stature subjects during the 5-year period from January 2005 to December 2009. The probability of receiving steroid treatment was < 10 % when the maximum cortisol concentration during an ITT was < 8.4 μg/dL. In the event of a suboptimal cortisol response during an ITT, only a single 1-μ g CST is recommended for assessment of adrenal function.
Original language | English (US) |
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Pages (from-to) | 733-739 |
Number of pages | 7 |
Journal | Journal of Pediatric Endocrinology and Metabolism |
Volume | 25 |
Issue number | 7-8 |
DOIs | |
State | Published - Aug 2012 |
Externally published | Yes |
Keywords
- Adrenal deficiency
- Adrenal sufficiency
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
- Pediatrics, Perinatology, and Child Health