Hormonal mediation of the analgesia produced by food deprivation

Robert J. Hamm, Janet S. Knisely, Ann Watson, Bruce G Lyeth, D. F B Bossut

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Research has demonstrated that a wide variety of environmental conditions are capable of producing analgesia. In the present experiment, the analgesia produced by 24 hr of food deprivation was examined following adrenalectomy, hypophysectomy, naltrexone (7 mg/kg), dexamethasone (0.4 mg/kg), or saline treatment. Results revealed that 24 hr of starvation elicited an analgesic response in the saline-treated and sham-operated groups. Naltrexone, dexamethasone, adrenalectomy, and hypophysectomy blocked the analgesia produced by food deprivation. The results demonstrate that 24 hr of food deprivation induced an opiate-mediated analgesic system that involves hormonal factors.

Original languageEnglish (US)
Pages (from-to)879-882
Number of pages4
JournalPhysiology and Behavior
Volume35
Issue number6
DOIs
StatePublished - 1985
Externally publishedYes

Fingerprint

Food Deprivation
Analgesia
Hypophysectomy
Naltrexone
Adrenalectomy
Dexamethasone
Analgesics
Opiate Alkaloids
Starvation
Research

Keywords

  • Adrenalectomy
  • Analgesia
  • Dexamethasone
  • Food deprivation
  • Hypophysectomy
  • Naltrexone
  • Stress-induced analgesia

ASJC Scopus subject areas

  • Physiology (medical)
  • Behavioral Neuroscience

Cite this

Hormonal mediation of the analgesia produced by food deprivation. / Hamm, Robert J.; Knisely, Janet S.; Watson, Ann; Lyeth, Bruce G; Bossut, D. F B.

In: Physiology and Behavior, Vol. 35, No. 6, 1985, p. 879-882.

Research output: Contribution to journalArticle

Hamm, Robert J. ; Knisely, Janet S. ; Watson, Ann ; Lyeth, Bruce G ; Bossut, D. F B. / Hormonal mediation of the analgesia produced by food deprivation. In: Physiology and Behavior. 1985 ; Vol. 35, No. 6. pp. 879-882.
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