Hormonal control of puberty

Research output: Chapter in Book/Report/Conference proceedingChapter


The process of puberty is part of an ongoing process that begins during fetal development and ends with sexual maturity. Early in gestation, GnRH secreting neurons gain functionality as a GnRH pulse generator. Pulsatile GnRH secretion results in pulsatile gonadotropin secretion, which ultimately leads to secretion of gonadal steroids. The pulse generator functions at a very low level of activity throughout most of childhood. Prior to pubertal onset, there is a decrease in GnRH inhibition. This results in an increased amplitude of gonadotropin pulses. In response, gonadal steroid levels rise and ultimately result in the development of secondary sexual characteristics.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Endocrine Diseases
Number of pages7
ISBN (Electronic)9780128122006
ISBN (Print)9780128121993
StatePublished - Jan 1 2018


  • Activin
  • Adrenarche
  • Antimüllerian hormone (AMH)
  • Estrogen
  • Follicle-stimulating hormone (FSH)
  • Follistatin
  • GnRH
  • Gonadarche
  • Gonadotropin
  • Inhibin
  • Leptin
  • Luteinizing hormone (LH)
  • Puberty
  • Testosterone

ASJC Scopus subject areas

  • Medicine(all)


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