Abstract
During the DNA-damage response, adaptor proteins mediate signaling between the PI3K-like sensor kinases, ATM and ATR, and serine/threonine effector kinases. Carballo et al. (2008) now show that the chromosomal protein Hop1 mediates PI3K-like kinase signaling during the repair of DNA double-strand breaks (DSBs) in meiosis.
Original language | English (US) |
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Pages (from-to) | 731-732 |
Number of pages | 2 |
Journal | Cell |
Volume | 132 |
Issue number | 5 |
DOIs | |
State | Published - Mar 7 2008 |
ASJC Scopus subject areas
- Cell Biology
- Molecular Biology