Abstract
During the DNA-damage response, adaptor proteins mediate signaling between the PI3K-like sensor kinases, ATM and ATR, and serine/threonine effector kinases. Carballo et al. (2008) now show that the chromosomal protein Hop1 mediates PI3K-like kinase signaling during the repair of DNA double-strand breaks (DSBs) in meiosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 731-732 |
| Number of pages | 2 |
| Journal | Cell |
| Volume | 132 |
| Issue number | 5 |
| DOIs | |
| State | Published - Mar 7 2008 |
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ASJC Scopus subject areas
- Cell Biology
- Molecular Biology
Cite this
Hop1 and the Meiotic DNA-Damage Response. / Hunter, Neil.
In: Cell, Vol. 132, No. 5, 07.03.2008, p. 731-732.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hop1 and the Meiotic DNA-Damage Response
AU - Hunter, Neil
PY - 2008/3/7
Y1 - 2008/3/7
N2 - During the DNA-damage response, adaptor proteins mediate signaling between the PI3K-like sensor kinases, ATM and ATR, and serine/threonine effector kinases. Carballo et al. (2008) now show that the chromosomal protein Hop1 mediates PI3K-like kinase signaling during the repair of DNA double-strand breaks (DSBs) in meiosis.
AB - During the DNA-damage response, adaptor proteins mediate signaling between the PI3K-like sensor kinases, ATM and ATR, and serine/threonine effector kinases. Carballo et al. (2008) now show that the chromosomal protein Hop1 mediates PI3K-like kinase signaling during the repair of DNA double-strand breaks (DSBs) in meiosis.
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UR - http://www.scopus.com/inward/citedby.url?scp=39749097930&partnerID=8YFLogxK
U2 - 10.1016/j.cell.2008.02.026
DO - 10.1016/j.cell.2008.02.026
M3 - Article
C2 - 18329359
AN - SCOPUS:39749097930
VL - 132
SP - 731
EP - 732
JO - Cell
JF - Cell
SN - 0092-8674
IS - 5
ER -