Hop1 and the Meiotic DNA-Damage Response

Neil Hunter

doi:10.1016/j.cell.2008.02.026

Hop1 and the Meiotic DNA-Damage Response

Neil Hunter

Cell Biology and Human Anatomy

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

During the DNA-damage response, adaptor proteins mediate signaling between the PI3K-like sensor kinases, ATM and ATR, and serine/threonine effector kinases. Carballo et al. (2008) now show that the chromosomal protein Hop1 mediates PI3K-like kinase signaling during the repair of DNA double-strand breaks (DSBs) in meiosis.

Original language	English (US)
Pages (from-to)	731-732
Number of pages	2
Journal	Cell
Volume	132
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2008.02.026
State	Published - Mar 7 2008

ASJC Scopus subject areas

Cell Biology
Molecular Biology

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title = "Hop1 and the Meiotic DNA-Damage Response",

abstract = "During the DNA-damage response, adaptor proteins mediate signaling between the PI3K-like sensor kinases, ATM and ATR, and serine/threonine effector kinases. Carballo et al. (2008) now show that the chromosomal protein Hop1 mediates PI3K-like kinase signaling during the repair of DNA double-strand breaks (DSBs) in meiosis.",

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AB - During the DNA-damage response, adaptor proteins mediate signaling between the PI3K-like sensor kinases, ATM and ATR, and serine/threonine effector kinases. Carballo et al. (2008) now show that the chromosomal protein Hop1 mediates PI3K-like kinase signaling during the repair of DNA double-strand breaks (DSBs) in meiosis.

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Hop1 and the Meiotic DNA-Damage Response

Abstract

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