Histophilus somni myocarditis and leptomeningitis in feedlot cattle: case report and occurrence in South America

Carlos A. Margineda, Donal O’Toole, Mónica Prieto, Francisco A. Uzal, Gustavo C. Zielinski

Research output: Contribution to journalArticle


We investigated deaths in a group of feedlot steers in Argentina. The main findings in 3 steers autopsied were pulmonary congestion and edema, necrotizing myocarditis, pericarditis, suppurative leptomeningitis, and bronchopneumonia. Histophilus somni was detected by bacterial culture and immunohistochemistry in the hearts of the 3 animals. Partial sequences of the 16S rRNA gene of a H. somni isolate had 99% similarity with other H. somni sequences in GenBank. Most reports of H. somni septicemia in cattle originate from North America and western Europe. There is scant information about cardiac histophilosis in South America. A survey of diagnostic laboratory personnel in 7 South American countries documented various forms of bovine histophilosis in Argentina, Brazil, Uruguay, and Venezuela.

Original languageEnglish (US)
Pages (from-to)893-898
Number of pages6
JournalJournal of Veterinary Diagnostic Investigation
Issue number6
StatePublished - Nov 1 2019



  • bovine
  • Histophilus somni
  • meningitis
  • myocarditis
  • pneumonia
  • sudden death

ASJC Scopus subject areas

  • veterinary(all)

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