Histopathology of the brain-stem nuclei of horses with "Mal seco", an equine dysautonomia

Francisco A Uzal, D. L. Doxey, C. A. Robles, M. P. Woodman, E. M. Milne

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


"Mal seco" is a disease of unknown aetiology affecting horses in Argentina. It is similar to grass sickness, a primary dysautonomia of horses in Europe. A histopathological study of the brain stem nuclei of three horses with "mal seco" was performed. Changes were found that consisted of chromatolysis, cytoplasmic vacuoles, eosinophilic sphaeroids, and pyknotic and eccentric nuclei. These changes were most severe at the oculomotor, vestibular and abducent nuclei. The results provide further evidence to suggest that "mal seco" and grass sickness may be the same disease.

Original languageEnglish (US)
Pages (from-to)297-301
Number of pages5
JournalJournal of Comparative Pathology
Issue number3
StatePublished - 1994
Externally publishedYes

ASJC Scopus subject areas

  • Animal Science and Zoology


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