Histopathology of nymphal pentastomid infections (Sebekia mississippiensis) in paratenic hosts

Walter M Boyce, E. A. Kazacos

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The histopathologic alterations occurring in mice, hamsters, turtles, and a frog were described following experimental infection with nymphs of Sebekia mississippiensis. Initially, nymphal migration caused traumatic tissue damage and hemorrhage characteristic of larva migrans. Subsequent inflammatory responses included cellular infiltration with eosinophils, macrophages, and lymphocytes, and fibrotic encapsulation of the nymphs. Dead nymphs were surrounded by a necrotic granulomatous response similar to that reported previously in humans and other animals. Differences were not seen in animals given single or multiple infections, but mice and hamsters exhibited a more marked inflammatory response than turtles. Overall, the histopathologic response to nymphal infections resembled those seen in infections resulting from ingestion of eggs, and both sources of infection should be considered in epidemiologic investigations of naturally occurring pentastomiasis.

Original languageEnglish (US)
Pages (from-to)104-110
Number of pages7
JournalJournal of Parasitology
Volume77
Issue number1
StatePublished - 1991
Externally publishedYes

Fingerprint

Pentastomida
paratenic hosts
histopathology
Nymph
nymphs
Infection
Turtles
infection
hamsters
turtle
Cricetinae
turtles
inflammation
Larva Migrans
larva migrans
encapsulation
animal
mice
eosinophils
Eosinophils

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Parasitology
  • Microbiology

Cite this

Histopathology of nymphal pentastomid infections (Sebekia mississippiensis) in paratenic hosts. / Boyce, Walter M; Kazacos, E. A.

In: Journal of Parasitology, Vol. 77, No. 1, 1991, p. 104-110.

Research output: Contribution to journalArticle

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