Abstract
Purpose of review: Sophisticated descriptions of the highly specialized vocal fold microarchitecture have been available for over three decades, but how this anatomy evolves with growth and aging remains an area of active investigation and, at times, a source of controversy. As our aging population expands and interest in pediatric voice disorders blossoms, it is timely to consider our contemporary understanding of evolving vocal fold histology and its implications for voice production. Recent findings: Novel applications of existing and emerging biotechnology, development of animal models and skillful use of human specimens have afforded greater insights into the histologic vocal fold changes seen throughout the lifespan in health and disease. Summary: Burgeoning knowledge has laid the foundation for more comprehensive models of vocal fold histology and has led to the development of innovative therapies for challenging voice disorders.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 460-465 |
| Number of pages | 6 |
| Journal | Current Opinion in Otolaryngology and Head and Neck Surgery |
| Volume | 22 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jan 1 2014 |
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Keywords
- Aging
- Development
- Extracellular matrix
- Lamina propria
- Vocal fold histology
ASJC Scopus subject areas
- Otorhinolaryngology
- Surgery
- Medicine(all)
Cite this
Histological changes in vocal fold growth and aging. / Kuhn, Maggie.
In: Current Opinion in Otolaryngology and Head and Neck Surgery, Vol. 22, No. 6, 01.01.2014, p. 460-465.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Histological changes in vocal fold growth and aging
AU - Kuhn, Maggie
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Purpose of review: Sophisticated descriptions of the highly specialized vocal fold microarchitecture have been available for over three decades, but how this anatomy evolves with growth and aging remains an area of active investigation and, at times, a source of controversy. As our aging population expands and interest in pediatric voice disorders blossoms, it is timely to consider our contemporary understanding of evolving vocal fold histology and its implications for voice production. Recent findings: Novel applications of existing and emerging biotechnology, development of animal models and skillful use of human specimens have afforded greater insights into the histologic vocal fold changes seen throughout the lifespan in health and disease. Summary: Burgeoning knowledge has laid the foundation for more comprehensive models of vocal fold histology and has led to the development of innovative therapies for challenging voice disorders.
AB - Purpose of review: Sophisticated descriptions of the highly specialized vocal fold microarchitecture have been available for over three decades, but how this anatomy evolves with growth and aging remains an area of active investigation and, at times, a source of controversy. As our aging population expands and interest in pediatric voice disorders blossoms, it is timely to consider our contemporary understanding of evolving vocal fold histology and its implications for voice production. Recent findings: Novel applications of existing and emerging biotechnology, development of animal models and skillful use of human specimens have afforded greater insights into the histologic vocal fold changes seen throughout the lifespan in health and disease. Summary: Burgeoning knowledge has laid the foundation for more comprehensive models of vocal fold histology and has led to the development of innovative therapies for challenging voice disorders.
KW - Aging
KW - Development
KW - Extracellular matrix
KW - Lamina propria
KW - Vocal fold histology
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UR - http://www.scopus.com/inward/citedby.url?scp=84927697959&partnerID=8YFLogxK
U2 - 10.1097/MOO.0000000000000108
DO - 10.1097/MOO.0000000000000108
M3 - Review article
C2 - 25232935
AN - SCOPUS:84927697959
VL - 22
SP - 460
EP - 465
JO - Current Opinion in Otolaryngology and Head and Neck Surgery
JF - Current Opinion in Otolaryngology and Head and Neck Surgery
SN - 1068-9508
IS - 6
ER -