Highly efficient chemoenzymatic synthesis of β1-3-linked galactosides

Hai Yu, Vireak Thon, Kam Lau, Li Cai, Yi Chen, Shengmao Mu, Yanhong Li, Peng George Wang, Xi Chen

Research output: Contribution to journalArticle

47 Scopus citations

Abstract

A novel d-galactosyl-β1-3-N-acetyl-d-hexosamine phosphorylase cloned from Bifidobacterium infantis (BiGalHexNAcP) was used with a recombinant E. coli K-12 galactokinase (GalK) for efficient one-pot two-enzyme synthesis of T-antigens, galacto-N-biose (Galβ1-3GalNAc), lacto-N-biose (Galβ1-3GlcNAc), and their derivatives.

Original languageEnglish (US)
Pages (from-to)7507-7509
Number of pages3
JournalChemical Communications
Volume46
Issue number40
DOIs
Publication statusPublished - Oct 28 2010

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ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

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