High-throughput screening of small-molecule microarrays with label-free optical scanning microscope

Y. Y. Fei, J. P. Landry, Y. S. Sun, X. B. Wang, Juntao T Luo, K. S. Lam, Xiangdong Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We investigated surface chemistry platforms for immobilizing two types of synthetic, small-molecule compound libraries, each with over 6000 compounds, and for screening these compounds for potential proteins ligands by a label-free optical scanning microscope.

Original languageEnglish (US)
Title of host publicationConference on Lasers and Electro-Optics, CLEO 2009
PublisherOptical Society of America (OSA)
ISBN (Print)9781557528698
DOIs
StatePublished - 2009
EventConference on Lasers and Electro-Optics, CLEO 2009 - Baltimore, MD, United States
Duration: May 31 2009Jun 5 2009

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Other

OtherConference on Lasers and Electro-Optics, CLEO 2009
CountryUnited States
CityBaltimore, MD
Period5/31/096/5/09

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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  • Cite this

    Fei, Y. Y., Landry, J. P., Sun, Y. S., Wang, X. B., Luo, J. T., Lam, K. S., & Zhu, X. (2009). High-throughput screening of small-molecule microarrays with label-free optical scanning microscope. In Conference on Lasers and Electro-Optics, CLEO 2009 (Optics InfoBase Conference Papers). Optical Society of America (OSA). https://doi.org/10.1364/cleo.2009.cfl3