High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes

J. P. Landry, Y. S. Sun, Y. Y. Fei, Kit Lam, X. D. Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The potential of biomolecular microarrays on glass for high-throughput kinetics assays has not previously been fully exploited. We demonstrate real-time label-free optical detection of antibodies binding to drug-antigen microarrays using oblique-incidence reflectivity difference (OI-RD) microscopes.

Original languageEnglish (US)
Title of host publicationOptics InfoBase Conference Papers
PublisherOptical Society of America
ISBN (Print)9781557528599
StatePublished - 2008
EventConference on Lasers and Electro-Optics, CLEO 2008 - San Jose, CA, United States
Duration: May 4 2008May 9 2008

Other

OtherConference on Lasers and Electro-Optics, CLEO 2008
CountryUnited States
CitySan Jose, CA
Period5/4/085/9/08

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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  • Cite this

    Landry, J. P., Sun, Y. S., Fei, Y. Y., Lam, K., & Zhu, X. D. (2008). High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes. In Optics InfoBase Conference Papers Optical Society of America.