High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes

J. P. Landry; Y. S. Sun; Y. Y. Fei; Kit Lam; X. D. Zhu

High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes

J. P. Landry, Y. S. Sun, Y. Y. Fei, Kit Lam, X. D. Zhu

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The potential of biomolecular microarrays on glass for high-throughput kinetics assays has not previously been fully exploited. We demonstrate real-time label-free optical detection of antibodies binding to drug-antigen microarrays using oblique-incidence reflectivity difference (OI-RD) microscopes.

Original language	English (US)
Title of host publication	Optics InfoBase Conference Papers
Publisher	Optical Society of America
ISBN (Print)	9781557528599
State	Published - 2008
Event	Conference on Lasers and Electro-Optics, CLEO 2008 - San Jose, CA, United States Duration: May 4 2008 → May 9 2008

Other

Other	Conference on Lasers and Electro-Optics, CLEO 2008
Country	United States
City	San Jose, CA
Period	5/4/08 → 5/9/08

ASJC Scopus subject areas

Instrumentation
Atomic and Molecular Physics, and Optics

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@inproceedings{c328ea6ade8d4eb286b6e109076fc510,

title = "High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes",

abstract = "The potential of biomolecular microarrays on glass for high-throughput kinetics assays has not previously been fully exploited. We demonstrate real-time label-free optical detection of antibodies binding to drug-antigen microarrays using oblique-incidence reflectivity difference (OI-RD) microscopes.",

author = "Landry, {J. P.} and Sun, {Y. S.} and Fei, {Y. Y.} and Kit Lam and Zhu, {X. D.}",

year = "2008",

language = "English (US)",

isbn = "9781557528599",

booktitle = "Optics InfoBase Conference Papers",

publisher = "Optical Society of America",

note = "Conference on Lasers and Electro-Optics, CLEO 2008 ; Conference date: 04-05-2008 Through 09-05-2008",

}

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T1 - High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes

AU - Landry, J. P.

AU - Sun, Y. S.

AU - Fei, Y. Y.

AU - Lam, Kit

AU - Zhu, X. D.

PY - 2008

Y1 - 2008

N2 - The potential of biomolecular microarrays on glass for high-throughput kinetics assays has not previously been fully exploited. We demonstrate real-time label-free optical detection of antibodies binding to drug-antigen microarrays using oblique-incidence reflectivity difference (OI-RD) microscopes.

AB - The potential of biomolecular microarrays on glass for high-throughput kinetics assays has not previously been fully exploited. We demonstrate real-time label-free optical detection of antibodies binding to drug-antigen microarrays using oblique-incidence reflectivity difference (OI-RD) microscopes.

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UR - http://www.scopus.com/inward/citedby.url?scp=84898635052&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:84898635052

SN - 9781557528599

BT - Optics InfoBase Conference Papers

PB - Optical Society of America

T2 - Conference on Lasers and Electro-Optics, CLEO 2008

Y2 - 4 May 2008 through 9 May 2008

ER -