High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes

J. P. Landry, Y. S. Sun, Y. Y. Fei, Kit Lam, X. D. Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The potential of biomolecular microarrays on glass for high-throughput kinetics assays has not previously been fully exploited. We demonstrate real-time label-free optical detection of antibodies binding to drug-antigen microarrays using oblique-incidence reflectivity difference (OI-RD) microscopes.

Original languageEnglish (US)
Title of host publication2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS
DOIs
StatePublished - 2008
EventConference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS 2008 - San Jose, CA, United States
Duration: May 4 2008May 9 2008

Other

OtherConference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS 2008
CountryUnited States
CitySan Jose, CA
Period5/4/085/9/08

Fingerprint

Microarrays
Labels
Microscopes
Throughput
Kinetics
Antigens
Antibodies
Assays
Glass
Pharmaceutical Preparations
Protein Binding

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

Cite this

Landry, J. P., Sun, Y. S., Fei, Y. Y., Lam, K., & Zhu, X. D. (2008). High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes. In 2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS [4550965] https://doi.org/10.1109/CLEO.2008.4550965

High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes. / Landry, J. P.; Sun, Y. S.; Fei, Y. Y.; Lam, Kit; Zhu, X. D.

2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS. 2008. 4550965.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Landry, JP, Sun, YS, Fei, YY, Lam, K & Zhu, XD 2008, High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes. in 2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS., 4550965, Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS 2008, San Jose, CA, United States, 5/4/08. https://doi.org/10.1109/CLEO.2008.4550965
Landry JP, Sun YS, Fei YY, Lam K, Zhu XD. High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes. In 2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS. 2008. 4550965 https://doi.org/10.1109/CLEO.2008.4550965
Landry, J. P. ; Sun, Y. S. ; Fei, Y. Y. ; Lam, Kit ; Zhu, X. D. / High-throughput protein binding end-points and kinetics in microarrays using label-free OI-RD microscopes. 2008 Conference on Quantum Electronics and Laser Science Conference on Lasers and Electro-Optics, CLEO/QELS. 2008.
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