High-throughput endpoint and real-time detection of biochemical reactions in microarrays using label-free oblique-incidence reflectivity difference microscopes

J. P. Landry, Y. S. Sun, Kit Lam, X. D. Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We describe recently developed oblique-incidence reflectivity difference microscopes, a form of polarization-modulated imaging ellipsometry, for label-free detection of biochemical reactions in microarrays. Configurations enabling high-throughput endpoint and real-time detection on glass substrates are discussed.

Original languageEnglish (US)
Title of host publicationOptics InfoBase Conference Papers
PublisherOptical Society of America
ISBN (Print)1557528349, 9781557528346
StatePublished - 2007
EventConference on Lasers and Electro-Optics, CLEO 2007 - Baltimore, MD, United States
Duration: May 6 2007May 6 2007

Other

OtherConference on Lasers and Electro-Optics, CLEO 2007
CountryUnited States
CityBaltimore, MD
Period5/6/075/6/07

Fingerprint

Ellipsometry
Microarrays
Labels
Microscopes
incidence
microscopes
Throughput
Polarization
reflectance
Imaging techniques
Glass
Substrates
ellipsometry
glass
polarization
configurations

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

Cite this

Landry, J. P., Sun, Y. S., Lam, K., & Zhu, X. D. (2007). High-throughput endpoint and real-time detection of biochemical reactions in microarrays using label-free oblique-incidence reflectivity difference microscopes. In Optics InfoBase Conference Papers Optical Society of America.

High-throughput endpoint and real-time detection of biochemical reactions in microarrays using label-free oblique-incidence reflectivity difference microscopes. / Landry, J. P.; Sun, Y. S.; Lam, Kit; Zhu, X. D.

Optics InfoBase Conference Papers. Optical Society of America, 2007.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Landry, JP, Sun, YS, Lam, K & Zhu, XD 2007, High-throughput endpoint and real-time detection of biochemical reactions in microarrays using label-free oblique-incidence reflectivity difference microscopes. in Optics InfoBase Conference Papers. Optical Society of America, Conference on Lasers and Electro-Optics, CLEO 2007, Baltimore, MD, United States, 5/6/07.
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