High-speed, high resolution OCT imaging of the retina with frequency swept lasers at 850 nm

Vivek Srinivasan, R. Huber, I. Gorczynska, D. Adler, J. Y. Jiang, P. Reisen, A. E. Cable, J. G. Fujimoto

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Ophthalmie OCT was performed using a novel, compact external cavity semiconductor laser at ∼850 nm. Retinal imaging was demonstrated with a resolution of <7 microns in tissue at a speed of 16,000 axial scans per second. The coherence length of the laser is >10 mm, enabling an axial measurement range of ∼2.5 mm. Real-time display and data streaming capabilities enable video-rate imaging of the retina at >30 frames per second. High-definition and three-dimensional imaging were demonstrated on normal retinas. The resolution of <7 microns in the retina is, to our knowledge, the highest resolution achieved in the retina with swept source OCT to date. The long coherence length of the laser enables high-sensitivity measurements over a large axial measurement range. The speed of 16,000 axial scans per second is comparable to current spectrometer-based spectral/Fourier domain OCT systems. The low cost and small footprint of our laser (∼10 cm × 20 cm) may enable the development of OCT for novel applications. Further improvements in speed will be possible by using alternative scanning methods.

Original languageEnglish (US)
Title of host publicationOphthalmic Technologies XVII
Volume6426
DOIs
StatePublished - Aug 31 2007
Externally publishedYes
EventOphthalmic Technologies XVII - San Jose, CA, United States
Duration: Jan 20 2007Jan 23 2007

Other

OtherOphthalmic Technologies XVII
CountryUnited States
CitySan Jose, CA
Period1/20/071/23/07

ASJC Scopus subject areas

  • Engineering(all)

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    Srinivasan, V., Huber, R., Gorczynska, I., Adler, D., Jiang, J. Y., Reisen, P., Cable, A. E., & Fujimoto, J. G. (2007). High-speed, high resolution OCT imaging of the retina with frequency swept lasers at 850 nm. In Ophthalmic Technologies XVII (Vol. 6426). [642603] https://doi.org/10.1117/12.699433