Abstract
Although the parahippocampal cortex (PHc) is known to be critical for memory formation, little is known about what is encoded by this area. Using multi-voxel pattern analysis of high-resolution functional magnetic resonance imaging (MRI) data, we examined responses to blocks of categorically coherent stimuli and found that patterns of activity in PHc were selective for not only scenes, but also for other non-spatial object categories (e.g., faces and toys). This pattern of results was also found in the parahippocampal place area (PPA), indicating that this region is not sensitive exclusively to scenes. In contrast, neither the hippocampus nor perirhinal cortex (PRc) were found to be selective for category information. The results indicate that regions within the medial temporal lobe may support distinct functions, and that the PHc appears to be particularly sensitive to category-level information.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 536-541 |
| Number of pages | 6 |
| Journal | Hippocampus |
| Volume | 18 |
| Issue number | 6 |
| DOIs | |
| State | Published - 2008 |
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Keywords
- Encoding
- fMRI
- Memory
- Parahippocampal
- Perirhinal
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
High-resolution multi-voxel pattern analysis of category selectivity in the medial temporal lobes. / Diana, Rachel A.; Yonelinas, Andrew P.; Ranganath, Charan.
In: Hippocampus, Vol. 18, No. 6, 2008, p. 536-541.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - High-resolution multi-voxel pattern analysis of category selectivity in the medial temporal lobes
AU - Diana, Rachel A.
AU - Yonelinas, Andrew P.
AU - Ranganath, Charan
PY - 2008
Y1 - 2008
N2 - Although the parahippocampal cortex (PHc) is known to be critical for memory formation, little is known about what is encoded by this area. Using multi-voxel pattern analysis of high-resolution functional magnetic resonance imaging (MRI) data, we examined responses to blocks of categorically coherent stimuli and found that patterns of activity in PHc were selective for not only scenes, but also for other non-spatial object categories (e.g., faces and toys). This pattern of results was also found in the parahippocampal place area (PPA), indicating that this region is not sensitive exclusively to scenes. In contrast, neither the hippocampus nor perirhinal cortex (PRc) were found to be selective for category information. The results indicate that regions within the medial temporal lobe may support distinct functions, and that the PHc appears to be particularly sensitive to category-level information.
AB - Although the parahippocampal cortex (PHc) is known to be critical for memory formation, little is known about what is encoded by this area. Using multi-voxel pattern analysis of high-resolution functional magnetic resonance imaging (MRI) data, we examined responses to blocks of categorically coherent stimuli and found that patterns of activity in PHc were selective for not only scenes, but also for other non-spatial object categories (e.g., faces and toys). This pattern of results was also found in the parahippocampal place area (PPA), indicating that this region is not sensitive exclusively to scenes. In contrast, neither the hippocampus nor perirhinal cortex (PRc) were found to be selective for category information. The results indicate that regions within the medial temporal lobe may support distinct functions, and that the PHc appears to be particularly sensitive to category-level information.
KW - Encoding
KW - fMRI
KW - Memory
KW - Parahippocampal
KW - Perirhinal
UR - http://www.scopus.com/inward/record.url?scp=45149113441&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=45149113441&partnerID=8YFLogxK
U2 - 10.1002/hipo.20433
DO - 10.1002/hipo.20433
M3 - Article
C2 - 18446830
AN - SCOPUS:45149113441
VL - 18
SP - 536
EP - 541
JO - Hippocampus
JF - Hippocampus
SN - 1050-9631
IS - 6
ER -