High prevalence of low serum vitamin B12 in a multi-ethnic Israeli population

Y. Gielchinsky, D. Elstein, Ralph Green, J. W. Miller, Y. Elstein, N. Algur, A. Lahad, E. Shinar, A. Abrahamov, A. Zimran

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


This study ascertained serum vitamin B12 levels among patients with Gaucher disease and among healthy Israelis. Serum B12 and metabolites' levels were studied in consecutive adult patients with Gaucher disease not treated with enzyme plus Ashkenazi Jewish neighbour-controls, together with healthy blood-donor volunteers of various ethnicities. Each group showed a high incidence of low serum B12 concentrations, with a 22.3% incidence among Ashkenazi Jews and 40% among patients with Gaucher disease. These findings raise questions on the individual and community levels of serum B12. We recommend evaluation of B12 levels among geographically contingent peoples.

Original languageEnglish (US)
Pages (from-to)707-709
Number of pages3
JournalBritish Journal of Haematology
Issue number3
StatePublished - 2001


  • Environmental factors
  • Gaucher disease
  • Homocysteine
  • Methylmalonic acid
  • Vitamin B deficiency

ASJC Scopus subject areas

  • Hematology


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