High-frequency ventilation for non-invasive respiratory support of neonates

Bradley A. Yoder, K. H. Albertine, Donald Null

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


Non-invasive respiratory support is increasingly used in lieu of intubated ventilator support for the management of neonatal respiratory failure, particularly in very low birth weight infants at risk for bronchopulmonary dysplasia. The optimal approach and mode for non-invasive support remains uncertain. This article reviews the application of high-frequency ventilation for non-invasive respiratory support in neonates, including basic science studies on mechanics of gas exchange, animal model investigations, and a review of current clinical use in human neonates.

Original languageEnglish (US)
Pages (from-to)162-173
Number of pages12
JournalSeminars in Fetal and Neonatal Medicine
Issue number3
StatePublished - Jun 1 2016


  • High frequency
  • Neonatal
  • Non-invasive
  • Respiratory

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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