High failure rates in outpatient treatment of salpingitis with either tetracycline alone or penicillin/ampicillin combination

S. E. Thompson, C. Brooks, D. A. Eschenbach, M. R. Spence, S. Cheng, Richard L Sweet, W. M. McCormack

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Eight hundred twenty-five ambulatory women with a clinical diagnosis of salpingitis were randomized to a 10-day course of either penicillin/ampicillin or tetracycline. Forty-four percent of women had gonococcal salpingitis and 56% nongonococcal salpingitis. Overall, both regimens cured equal proportions of women: At 30 days, 81% were cured by penicillin/ampicillin and 82% by tetracycline. However, the proportion of women with gonococcal salpingitis cured by 30 days was significantly greater than that of women with nongonococcal salpingitis. By 30 days, 14% of women with gonococcal salpingitis and 21% of women with nongonococcal salpingitis were not cured by either regimen. These data suggest that both regimens were only marginally acceptable for women with gonococcal salpingitis and that neither regimen was acceptable for nongonococcal salpingitis.

Original languageEnglish (US)
Pages (from-to)635-641
Number of pages7
JournalAmerican Journal of Obstetrics and Gynecology
Volume152
Issue number6 I
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

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    Thompson, S. E., Brooks, C., Eschenbach, D. A., Spence, M. R., Cheng, S., Sweet, R. L., & McCormack, W. M. (1985). High failure rates in outpatient treatment of salpingitis with either tetracycline alone or penicillin/ampicillin combination. American Journal of Obstetrics and Gynecology, 152(6 I), 635-641.