Abstract
Heterotopic bone induced in mice by implantation of demineralized rat bone matrix does not respond to Moloney sarcoma. The biochemical and morphological parameters of osteogenesis (alkaline and acid phosphatase activity, 45Ca-uptake and total calcium content) are similar in the sites of Moloney sarcoma as in the contralateral, unexposed to the sarcoma, side. In contrast, periosteum of implants of syngeneic costal bone in response to Moloney sarcoma proliferates and produces new bone in the same manner, as orthotopic bones at the sites of Moloney sarcoma do. It is concluded that ectopically induced bones do not develop a true periosteum.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 583-593 |
| Number of pages | 11 |
| Journal | Archivum Immunologiae et Therapiae Experimentalis |
| Volume | 34 |
| Issue number | 5-6 |
| State | Published - 1986 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Immunology
Cite this
Heterotopically induced bone does not develop functional periosteal membrane. / Włodarski, K. H.; Reddi, A Hari.
In: Archivum Immunologiae et Therapiae Experimentalis, Vol. 34, No. 5-6, 1986, p. 583-593.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Heterotopically induced bone does not develop functional periosteal membrane.
AU - Włodarski, K. H.
AU - Reddi, A Hari
PY - 1986
Y1 - 1986
N2 - Heterotopic bone induced in mice by implantation of demineralized rat bone matrix does not respond to Moloney sarcoma. The biochemical and morphological parameters of osteogenesis (alkaline and acid phosphatase activity, 45Ca-uptake and total calcium content) are similar in the sites of Moloney sarcoma as in the contralateral, unexposed to the sarcoma, side. In contrast, periosteum of implants of syngeneic costal bone in response to Moloney sarcoma proliferates and produces new bone in the same manner, as orthotopic bones at the sites of Moloney sarcoma do. It is concluded that ectopically induced bones do not develop a true periosteum.
AB - Heterotopic bone induced in mice by implantation of demineralized rat bone matrix does not respond to Moloney sarcoma. The biochemical and morphological parameters of osteogenesis (alkaline and acid phosphatase activity, 45Ca-uptake and total calcium content) are similar in the sites of Moloney sarcoma as in the contralateral, unexposed to the sarcoma, side. In contrast, periosteum of implants of syngeneic costal bone in response to Moloney sarcoma proliferates and produces new bone in the same manner, as orthotopic bones at the sites of Moloney sarcoma do. It is concluded that ectopically induced bones do not develop a true periosteum.
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UR - http://www.scopus.com/inward/citedby.url?scp=0022855392&partnerID=8YFLogxK
M3 - Article
C2 - 3296997
AN - SCOPUS:0022855392
VL - 34
SP - 583
EP - 593
JO - Archivum Immunologiae et Therapiae Experimentalis
JF - Archivum Immunologiae et Therapiae Experimentalis
SN - 0004-069X
IS - 5-6
ER -