Abstract
Purpose of review: Herpes zoster is a common condition, and involvement of the trigeminal nerve results in herpes zoster ophthalmicus (HZO). Acute keratitis is one of the most common of these ocular complications associated with HZO. The findings associated with and the management of acute zoster keratitis will be reviewed. Recent findings: The incidence rate of herpes zoster has been on the rise over the past several decades. At the same time, the average patient age at presentation is declining with similar trends also seen in HZO. The cause of these changes has yet to be determined. Our understanding of corneal involvement in HZO continues to evolve with new imaging demonstrating viral particles within keratocytes in a case of zoster stromal keratitis. New medications such as topical ganciclovir are also helping to better manage acute zoster keratitis that is unresponsive to oral antiviral therapy. Summary: Acute zoster keratitis can lead to permanent vision loss. Early diagnosis and management may help reduce these potentially devastating complications. Oral and topical antiviral medications can play a role in managing the acute disease, and herpes zoster vaccinations are important for prevention of disease. Further research must be done to establish standards for treatment of anterior segment complications from herpes zoster.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 328-333 |
| Number of pages | 6 |
| Journal | Current Opinion in Ophthalmology |
| Volume | 29 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jul 1 2018 |
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Keywords
- acute keratitis
- herpes zoster ophthalmicus
- zoster vaccine
ASJC Scopus subject areas
- Ophthalmology
Cite this
Herpes zoster ophthalmicus : Acute keratitis. / Li, Jennifer.
In: Current Opinion in Ophthalmology, Vol. 29, No. 4, 01.07.2018, p. 328-333.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Herpes zoster ophthalmicus
T2 - Acute keratitis
AU - Li, Jennifer
PY - 2018/7/1
Y1 - 2018/7/1
N2 - Purpose of review: Herpes zoster is a common condition, and involvement of the trigeminal nerve results in herpes zoster ophthalmicus (HZO). Acute keratitis is one of the most common of these ocular complications associated with HZO. The findings associated with and the management of acute zoster keratitis will be reviewed. Recent findings: The incidence rate of herpes zoster has been on the rise over the past several decades. At the same time, the average patient age at presentation is declining with similar trends also seen in HZO. The cause of these changes has yet to be determined. Our understanding of corneal involvement in HZO continues to evolve with new imaging demonstrating viral particles within keratocytes in a case of zoster stromal keratitis. New medications such as topical ganciclovir are also helping to better manage acute zoster keratitis that is unresponsive to oral antiviral therapy. Summary: Acute zoster keratitis can lead to permanent vision loss. Early diagnosis and management may help reduce these potentially devastating complications. Oral and topical antiviral medications can play a role in managing the acute disease, and herpes zoster vaccinations are important for prevention of disease. Further research must be done to establish standards for treatment of anterior segment complications from herpes zoster.
AB - Purpose of review: Herpes zoster is a common condition, and involvement of the trigeminal nerve results in herpes zoster ophthalmicus (HZO). Acute keratitis is one of the most common of these ocular complications associated with HZO. The findings associated with and the management of acute zoster keratitis will be reviewed. Recent findings: The incidence rate of herpes zoster has been on the rise over the past several decades. At the same time, the average patient age at presentation is declining with similar trends also seen in HZO. The cause of these changes has yet to be determined. Our understanding of corneal involvement in HZO continues to evolve with new imaging demonstrating viral particles within keratocytes in a case of zoster stromal keratitis. New medications such as topical ganciclovir are also helping to better manage acute zoster keratitis that is unresponsive to oral antiviral therapy. Summary: Acute zoster keratitis can lead to permanent vision loss. Early diagnosis and management may help reduce these potentially devastating complications. Oral and topical antiviral medications can play a role in managing the acute disease, and herpes zoster vaccinations are important for prevention of disease. Further research must be done to establish standards for treatment of anterior segment complications from herpes zoster.
KW - acute keratitis
KW - herpes zoster ophthalmicus
KW - zoster vaccine
UR - http://www.scopus.com/inward/record.url?scp=85049248277&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85049248277&partnerID=8YFLogxK
U2 - 10.1097/ICU.0000000000000491
DO - 10.1097/ICU.0000000000000491
M3 - Review article
C2 - 29794881
AN - SCOPUS:85049248277
VL - 29
SP - 328
EP - 333
JO - Current Opinion in Ophthalmology
JF - Current Opinion in Ophthalmology
SN - 1040-8738
IS - 4
ER -