Herd-level prevalence of Mycobacterium avium subsp. paratuberculosis infection in United States dairy herds in 2007

J. E. Lombard, Ian Gardner, S. R. Jafarzadeh, C. P. Fossler, B. Harris, R. T. Capsel, B. A. Wagner, W. O. Johnson

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Testing of composite fecal (environmental) samples from high traffic areas in dairy herds has been shown to be a cost-effective and sensitive method for classification of herd status for Mycobacterium avium subsp. paratuberculosis (MAP). In the National Animal Health Monitoring System's (NAHMS) Dairy 2007 study, the apparent herd-level prevalence of MAP was 70.4% (369/524 had ≥1 culture-positive composite fecal samples out of 6 tested). Based on these data, the true herd-level prevalence (HP) of MAP infection was estimated using Bayesian methods adjusting for the herd sensitivity (HSe) and herd specificity (HSp) of the test method. The Bayesian prior for HSe of composite fecal cultures was based on data from the NAHMS Dairy 2002 study and the prior for HSp was based on expert opinion. The posterior median HP (base model) was 91.1% (95% probability interval, 81.6 to 99.3%) and estimates were most sensitive to the prior for HSe. The HP was higher than estimated from the NAHMS Dairy 1996 and 2002 studies but estimates are not directly comparable with those of prior NAHMS studies because of the different testing methods and criteria used for herd classification.

Original languageEnglish (US)
Pages (from-to)234-238
Number of pages5
JournalPreventive Veterinary Medicine
Volume108
Issue number2-3
DOIs
StatePublished - Feb 1 2013
Externally publishedYes

Fingerprint

Paratuberculosis
Mycobacterium avium
Mycobacterium avium subsp. paratuberculosis
dairy herds
herds
Health
Infection
infection
Bayes Theorem
Expert Testimony
dairies
Costs and Cost Analysis
Sensitivity and Specificity
expert opinion
testing
Bayesian theory
traffic
methodology

Keywords

  • Composite fecal samples
  • Mycobacterium avium subsp. paratuberculosis
  • NAHMS
  • True herd-level prevalence

ASJC Scopus subject areas

  • Food Animals
  • Animal Science and Zoology

Cite this

Herd-level prevalence of Mycobacterium avium subsp. paratuberculosis infection in United States dairy herds in 2007. / Lombard, J. E.; Gardner, Ian; Jafarzadeh, S. R.; Fossler, C. P.; Harris, B.; Capsel, R. T.; Wagner, B. A.; Johnson, W. O.

In: Preventive Veterinary Medicine, Vol. 108, No. 2-3, 01.02.2013, p. 234-238.

Research output: Contribution to journalArticle

Lombard, J. E. ; Gardner, Ian ; Jafarzadeh, S. R. ; Fossler, C. P. ; Harris, B. ; Capsel, R. T. ; Wagner, B. A. ; Johnson, W. O. / Herd-level prevalence of Mycobacterium avium subsp. paratuberculosis infection in United States dairy herds in 2007. In: Preventive Veterinary Medicine. 2013 ; Vol. 108, No. 2-3. pp. 234-238.
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