Hepatic osteodystrophy in a golden lion tamarin (Leontopithecus rosalia)

Eun ju Choi, Sara E. Childs-Sanford, Noha Abou-Madi, Erin E. King, Brian G. Caserto, Heather Priest, Erica Behling-Kelly, Andrew D. Miller

Research output: Contribution to journalArticle

Abstract

An 8-yr-old, captive, female golden lion tamarin (Leontopithecus rosalia) with a 6-yr history of hyperbilirubinemia was examined for inappetence and weight loss. Physical examination and blood pressure monitoring under anesthesia revealed hypothermia and hypotension, and blood work revealed hypoglycemia, markedly elevated liver enzymes, including serum alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase, and confirmed the hyperbilirubinemia. A complete blood count suggested chronic lymphoid leukemia. The animal's condition deteriorated during recovery, and the animal died despite aggressive treatment. Grossly, there was micronodular cirrhosis of the liver, severe icterus, and diffuse osteopenia of all examined bones. Microscopic examination of the liver confirmed the micronodular cirrhosis and bone lesions were compatible with diffuse osteopenia and osteomalacia. This brief communication presents a case of chronic liver disease and lesions indicative of metabolic bone disease, also known as hepatic osteodystrophy. To the authors' knowledge, this is the first documented case of hepatic osteodystrophy in the veterinary literature.

Original languageEnglish (US)
Pages (from-to)907-911
Number of pages5
JournalJournal of Zoo and Wildlife Medicine
Volume47
Issue number3
DOIs
StatePublished - Sep 1 2016
Externally publishedYes

Fingerprint

Leontopithecus
Leontopithecus rosalia
Metabolic Bone Diseases
hyperbilirubinemia
osteopenia
liver
Hyperbilirubinemia
Liver
lesions (animal)
bones
osteomalacia
developmental orthopedic disease
Lymphoid Leukemia
Bone and Bones
Osteomalacia
jaundice
liver cirrhosis
Blood Cell Count
hypoglycemia
hypothermia

Keywords

  • Cirrhosis
  • Golden lion tamarin
  • hepatic osteodystrophy
  • hyperbilirubinemia
  • Leontopithecus rosalia

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Choi, E. J., Childs-Sanford, S. E., Abou-Madi, N., King, E. E., Caserto, B. G., Priest, H., ... Miller, A. D. (2016). Hepatic osteodystrophy in a golden lion tamarin (Leontopithecus rosalia). Journal of Zoo and Wildlife Medicine, 47(3), 907-911. https://doi.org/10.1638/2015-0201.1

Hepatic osteodystrophy in a golden lion tamarin (Leontopithecus rosalia). / Choi, Eun ju; Childs-Sanford, Sara E.; Abou-Madi, Noha; King, Erin E.; Caserto, Brian G.; Priest, Heather; Behling-Kelly, Erica; Miller, Andrew D.

In: Journal of Zoo and Wildlife Medicine, Vol. 47, No. 3, 01.09.2016, p. 907-911.

Research output: Contribution to journalArticle

Choi, EJ, Childs-Sanford, SE, Abou-Madi, N, King, EE, Caserto, BG, Priest, H, Behling-Kelly, E & Miller, AD 2016, 'Hepatic osteodystrophy in a golden lion tamarin (Leontopithecus rosalia)', Journal of Zoo and Wildlife Medicine, vol. 47, no. 3, pp. 907-911. https://doi.org/10.1638/2015-0201.1
Choi EJ, Childs-Sanford SE, Abou-Madi N, King EE, Caserto BG, Priest H et al. Hepatic osteodystrophy in a golden lion tamarin (Leontopithecus rosalia). Journal of Zoo and Wildlife Medicine. 2016 Sep 1;47(3):907-911. https://doi.org/10.1638/2015-0201.1
Choi, Eun ju ; Childs-Sanford, Sara E. ; Abou-Madi, Noha ; King, Erin E. ; Caserto, Brian G. ; Priest, Heather ; Behling-Kelly, Erica ; Miller, Andrew D. / Hepatic osteodystrophy in a golden lion tamarin (Leontopithecus rosalia). In: Journal of Zoo and Wildlife Medicine. 2016 ; Vol. 47, No. 3. pp. 907-911.
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