Hemodynamic effects of argon pneumoperitoneum

D. M. Eisenhauer, C. J. Saunders, Hung S Ho, B. M. Wolfe

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The hemodynamic effects of argon pneumoperitoneum were studied to define its possible role as an alternative gas for intraperitoneal insufflation during minimally invasive surgery. Adult pigs were anesthetized and placed on mechanical ventilation. Parameters measured or determined included mean arterial (MAP), pulmonary arterial (PAP), pulmonary arterial wedge (PAWP), right atrial (CVP), and inferior vena cava venous (IVC) pressures, total excretion of CO2 (VCO2), oxygen consumption (VO2), minute ventilation, and arterial blood gases. Also determined were cardiac output, stroke volume, and systemic vascular resistance all indexed to weight (CI, SVI, SVRI). Data were recorded during a 1-h baseline, 2 h of insufflation with argon gas at a constant pressure of 15 mmHg, and 1 h recovery after desufflation. There was no significant change from baseline in VCO2, VO2, MAP, PAP, PAWP, CVP, PaCO2, or arterial pH. Argon pneumoperitoneum significantly increased systemic vascular resistance index and exerted a depressant effect on stroke volume index and cardiac index by 25% and 30% from baseline values, respectively (P<0.05). Inferior vena cava pressure increased as a reflection of the intraabdominal pressure. Argon insufflation had no effect on respiratory function. Argon gas may not be physiologically inert, and in patients with cardiovascular disease its effects may be clinically important.

Original languageEnglish (US)
Pages (from-to)315-321
Number of pages7
JournalSurgical Endoscopy
Volume8
Issue number4
DOIs
StatePublished - Apr 1994

Fingerprint

Pneumoperitoneum
Argon
Hemodynamics
Insufflation
Gases
Inferior Vena Cava
Pressure
Vascular Resistance
Stroke Volume
Lung
Venous Pressure
Minimally Invasive Surgical Procedures
Artificial Respiration
Oxygen Consumption
Cardiac Output
Ventilation
Cardiovascular Diseases
Swine
Weights and Measures

Keywords

  • Argon beam
  • Argon gas
  • Hemodynamics
  • Laparoscopy
  • Pneumoperitoneum

ASJC Scopus subject areas

  • Surgery

Cite this

Eisenhauer, D. M., Saunders, C. J., Ho, H. S., & Wolfe, B. M. (1994). Hemodynamic effects of argon pneumoperitoneum. Surgical Endoscopy, 8(4), 315-321. https://doi.org/10.1007/BF00590961

Hemodynamic effects of argon pneumoperitoneum. / Eisenhauer, D. M.; Saunders, C. J.; Ho, Hung S; Wolfe, B. M.

In: Surgical Endoscopy, Vol. 8, No. 4, 04.1994, p. 315-321.

Research output: Contribution to journalArticle

Eisenhauer, DM, Saunders, CJ, Ho, HS & Wolfe, BM 1994, 'Hemodynamic effects of argon pneumoperitoneum', Surgical Endoscopy, vol. 8, no. 4, pp. 315-321. https://doi.org/10.1007/BF00590961
Eisenhauer, D. M. ; Saunders, C. J. ; Ho, Hung S ; Wolfe, B. M. / Hemodynamic effects of argon pneumoperitoneum. In: Surgical Endoscopy. 1994 ; Vol. 8, No. 4. pp. 315-321.
@article{999096ecc7d74c5a9f87c488bbb76a6f,
title = "Hemodynamic effects of argon pneumoperitoneum",
abstract = "The hemodynamic effects of argon pneumoperitoneum were studied to define its possible role as an alternative gas for intraperitoneal insufflation during minimally invasive surgery. Adult pigs were anesthetized and placed on mechanical ventilation. Parameters measured or determined included mean arterial (MAP), pulmonary arterial (PAP), pulmonary arterial wedge (PAWP), right atrial (CVP), and inferior vena cava venous (IVC) pressures, total excretion of CO2 (VCO2), oxygen consumption (VO2), minute ventilation, and arterial blood gases. Also determined were cardiac output, stroke volume, and systemic vascular resistance all indexed to weight (CI, SVI, SVRI). Data were recorded during a 1-h baseline, 2 h of insufflation with argon gas at a constant pressure of 15 mmHg, and 1 h recovery after desufflation. There was no significant change from baseline in VCO2, VO2, MAP, PAP, PAWP, CVP, PaCO2, or arterial pH. Argon pneumoperitoneum significantly increased systemic vascular resistance index and exerted a depressant effect on stroke volume index and cardiac index by 25{\%} and 30{\%} from baseline values, respectively (P<0.05). Inferior vena cava pressure increased as a reflection of the intraabdominal pressure. Argon insufflation had no effect on respiratory function. Argon gas may not be physiologically inert, and in patients with cardiovascular disease its effects may be clinically important.",
keywords = "Argon beam, Argon gas, Hemodynamics, Laparoscopy, Pneumoperitoneum",
author = "Eisenhauer, {D. M.} and Saunders, {C. J.} and Ho, {Hung S} and Wolfe, {B. M.}",
year = "1994",
month = "4",
doi = "10.1007/BF00590961",
language = "English (US)",
volume = "8",
pages = "315--321",
journal = "Surgical Endoscopy and Other Interventional Techniques",
issn = "0930-2794",
publisher = "Springer New York",
number = "4",

}

TY - JOUR

T1 - Hemodynamic effects of argon pneumoperitoneum

AU - Eisenhauer, D. M.

AU - Saunders, C. J.

AU - Ho, Hung S

AU - Wolfe, B. M.

PY - 1994/4

Y1 - 1994/4

N2 - The hemodynamic effects of argon pneumoperitoneum were studied to define its possible role as an alternative gas for intraperitoneal insufflation during minimally invasive surgery. Adult pigs were anesthetized and placed on mechanical ventilation. Parameters measured or determined included mean arterial (MAP), pulmonary arterial (PAP), pulmonary arterial wedge (PAWP), right atrial (CVP), and inferior vena cava venous (IVC) pressures, total excretion of CO2 (VCO2), oxygen consumption (VO2), minute ventilation, and arterial blood gases. Also determined were cardiac output, stroke volume, and systemic vascular resistance all indexed to weight (CI, SVI, SVRI). Data were recorded during a 1-h baseline, 2 h of insufflation with argon gas at a constant pressure of 15 mmHg, and 1 h recovery after desufflation. There was no significant change from baseline in VCO2, VO2, MAP, PAP, PAWP, CVP, PaCO2, or arterial pH. Argon pneumoperitoneum significantly increased systemic vascular resistance index and exerted a depressant effect on stroke volume index and cardiac index by 25% and 30% from baseline values, respectively (P<0.05). Inferior vena cava pressure increased as a reflection of the intraabdominal pressure. Argon insufflation had no effect on respiratory function. Argon gas may not be physiologically inert, and in patients with cardiovascular disease its effects may be clinically important.

AB - The hemodynamic effects of argon pneumoperitoneum were studied to define its possible role as an alternative gas for intraperitoneal insufflation during minimally invasive surgery. Adult pigs were anesthetized and placed on mechanical ventilation. Parameters measured or determined included mean arterial (MAP), pulmonary arterial (PAP), pulmonary arterial wedge (PAWP), right atrial (CVP), and inferior vena cava venous (IVC) pressures, total excretion of CO2 (VCO2), oxygen consumption (VO2), minute ventilation, and arterial blood gases. Also determined were cardiac output, stroke volume, and systemic vascular resistance all indexed to weight (CI, SVI, SVRI). Data were recorded during a 1-h baseline, 2 h of insufflation with argon gas at a constant pressure of 15 mmHg, and 1 h recovery after desufflation. There was no significant change from baseline in VCO2, VO2, MAP, PAP, PAWP, CVP, PaCO2, or arterial pH. Argon pneumoperitoneum significantly increased systemic vascular resistance index and exerted a depressant effect on stroke volume index and cardiac index by 25% and 30% from baseline values, respectively (P<0.05). Inferior vena cava pressure increased as a reflection of the intraabdominal pressure. Argon insufflation had no effect on respiratory function. Argon gas may not be physiologically inert, and in patients with cardiovascular disease its effects may be clinically important.

KW - Argon beam

KW - Argon gas

KW - Hemodynamics

KW - Laparoscopy

KW - Pneumoperitoneum

UR - http://www.scopus.com/inward/record.url?scp=0028411793&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028411793&partnerID=8YFLogxK

U2 - 10.1007/BF00590961

DO - 10.1007/BF00590961

M3 - Article

C2 - 8209302

AN - SCOPUS:0028411793

VL - 8

SP - 315

EP - 321

JO - Surgical Endoscopy and Other Interventional Techniques

JF - Surgical Endoscopy and Other Interventional Techniques

SN - 0930-2794

IS - 4

ER -