Helix packing in polytopic membrane proteins: The lactose permease of Escherichia coli

H. Ronald Kaback, John C Voss, Jianhua Wu

Research output: Contribution to journalArticlepeer-review

88 Scopus citations

Abstract

Recent advances in protein engineering have facilitated the development of alternative approaches to determine helix packing in polytopic membrane proteins. Using the lac permease as a paradigm, several site-directed biophysical and biochemical techniques are described which should be generally applicable.

Original languageEnglish (US)
Pages (from-to)537-542
Number of pages6
JournalCurrent Opinion in Structural Biology
Volume7
Issue number4
DOIs
StatePublished - Aug 1997
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Structural Biology

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