Heights and haematology: The story of haemoglobin at altitude

Jeremy S. Windsor, George W Rodway

Research output: Contribution to journalReview article

46 Scopus citations

Abstract

In order to compensate for the low partial pressure of oxygen at altitude, the human body undergoes a number of physiological changes. A vital component in this process is the increase in the concentration of circulating haemoglobin. The role of HIF-1α, erythropoietin and red blood cells in this acclimatisation process is described, together with the fall in plasma volume that increases the concentration of haemoglobin in the early stages of hypoxic exposure.

Original languageEnglish (US)
Pages (from-to)148-151
Number of pages4
JournalPostgraduate Medical Journal
Volume83
Issue number977
DOIs
StatePublished - Mar 2007
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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