Abstract
Simian immunodeficiency virus (SIV) infection disseminated into the oropharyngeal tissues of rhesus macaques 6 weeks following intravenous inoculation. Severe local CD4 + T-cell depletion coincided with increases in NK cell and proinflammatory biomarkers and the disruption of growth-associated gene transcription, demonstrating the rapid establishment of pathogenesis in the oral mucosa.
Original language | English (US) |
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Pages (from-to) | 277-281 |
Number of pages | 5 |
Journal | Clinical and Vaccine Immunology |
Volume | 16 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2009 |
ASJC Scopus subject areas
- Clinical Biochemistry
- Immunology
- Immunology and Allergy
- Microbiology (medical)