Head and Neck Paragangliomas

Michael Moore, James L. Netterville, William M. Mendenhall, Brandon Isaacson, Brian Nussenbaum

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Objective Head and neck paragangliomas are a group of slow-growing hypervascular tumors associated with the paraganglion system. The approach to evaluate and treat these lesions has evolved over the last 2 decades. While radical surgery had been the traditional approach, improvements in diagnostic imaging as well as radiation therapy techniques have led to an emphasis on observation and nonsurgical therapy in many patients. This article reviews the contemporary approach to the workup and management of head and neck paragangliomas. Data Source Articles were identified from PubMed. Review Methods PubMed searches with the following keywords were performed: carotid body paraganglioma management, vagal paraganglioma management, jugulotympanic paraganglioma management, imaging of head and neck paragangliomas, head and neck paraganglioma embolization, paraganglioma radiation, head and neck paraganglioma management, observation of head and neck paragangliomas, bilateral carotid body paragangliomas, and genetics of paragangliomas. Review and original research articles available in the English language and published during or after 2009 were selected on the basis of their clinical relevance and scientific strength. Certain articles published prior to 2009 were also included if they provided background information that was relevant. Conclusions/Implications for Practice Workup and treatment of head and neck paragangliomas are changing. With more now known regarding the longitudinal behavior of these tumors, observation and nonsurgical therapy are indicated in many instances. For patients where surgery is the most appropriate option, improved diagnostic and perioperative techniques are allowing patients to tolerate resection, often with reduced morbidity.

Original languageEnglish (US)
Pages (from-to)597-605
Number of pages9
JournalOtolaryngology - Head and Neck Surgery (United States)
Volume154
Issue number4
DOIs
StatePublished - Jan 1 2016
Externally publishedYes

Fingerprint

Paraganglioma
Neck
Head
Carotid Body Tumor
PubMed
Observation
Information Storage and Retrieval
Diagnostic Imaging
Neoplasms
Language
Radiotherapy
Therapeutics
Radiation

Keywords

  • carotid body paraganglioma
  • jugulare paraganglioma
  • paraganglioma
  • vagal paraganglioma

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Cite this

Moore, M., Netterville, J. L., Mendenhall, W. M., Isaacson, B., & Nussenbaum, B. (2016). Head and Neck Paragangliomas. Otolaryngology - Head and Neck Surgery (United States), 154(4), 597-605. https://doi.org/10.1177/0194599815627667

Head and Neck Paragangliomas. / Moore, Michael; Netterville, James L.; Mendenhall, William M.; Isaacson, Brandon; Nussenbaum, Brian.

In: Otolaryngology - Head and Neck Surgery (United States), Vol. 154, No. 4, 01.01.2016, p. 597-605.

Research output: Contribution to journalArticle

Moore, M, Netterville, JL, Mendenhall, WM, Isaacson, B & Nussenbaum, B 2016, 'Head and Neck Paragangliomas', Otolaryngology - Head and Neck Surgery (United States), vol. 154, no. 4, pp. 597-605. https://doi.org/10.1177/0194599815627667
Moore M, Netterville JL, Mendenhall WM, Isaacson B, Nussenbaum B. Head and Neck Paragangliomas. Otolaryngology - Head and Neck Surgery (United States). 2016 Jan 1;154(4):597-605. https://doi.org/10.1177/0194599815627667
Moore, Michael ; Netterville, James L. ; Mendenhall, William M. ; Isaacson, Brandon ; Nussenbaum, Brian. / Head and Neck Paragangliomas. In: Otolaryngology - Head and Neck Surgery (United States). 2016 ; Vol. 154, No. 4. pp. 597-605.
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