Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative

Peipei Ping, Åsa B. Gustafsson, Donald M Bers, Lothar A. Blatter, Hua Cai, Arshad Jahangir, Daniel Kelly, Deborah Muoio, Brian O'Rourke, Peter Rabinovitch, Natalia Trayanova, Jennifer Van Eyk, James N. Weiss, Renee Wong, Lisa Schwartz Longacre

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Mitochondrial biology is the sum of diverse phenomena from molecular profiles to physiological functions. A mechanistic understanding of mitochondria in disease development, and hence the future prospect of clinical translations, relies on a systems-level integration of expertise from multiple fields of investigation. Upon the successful conclusion of a recent National Institutes of Health, National Heart, Lung, and Blood Institute initiative on integrative mitochondrial biology in cardiovascular diseases, we reflect on the accomplishments made possible by this unique interdisciplinary collaboration effort and exciting new fronts on the study of these remarkable organelles.

Original languageEnglish (US)
Pages (from-to)234-238
Number of pages5
JournalCirculation Research
Volume117
Issue number3
DOIs
StatePublished - Jul 17 2015

Keywords

  • cardiovascular disease
  • cell death
  • heart diseases
  • mitochondria
  • National Heart, Lung, and Blood Institute (U.S.)

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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    Ping, P., Gustafsson, Å. B., Bers, D. M., Blatter, L. A., Cai, H., Jahangir, A., Kelly, D., Muoio, D., O'Rourke, B., Rabinovitch, P., Trayanova, N., Van Eyk, J., Weiss, J. N., Wong, R., & Longacre, L. S. (2015). Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative. Circulation Research, 117(3), 234-238. https://doi.org/10.1161/CIRCRESAHA.117.306693