Hair cells - Beyond the transducer

G. D. Housley, W. Marcotti, D. Navaratnam, E. N. Yamoah

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


This review considers the "tween twixt and twain" of hair cell physiology, specifically the signaling elements and membrane conductances which underpin forward and reverse transduction at the input stage of hair cell function and neurotransmitter release at the output stage. Other sections of this review series outline the advances which have been made in understanding the molecular physiology of mechanoelectrical transduction and outer hair cell electromotility. Here we outline the contributions of a considerable array of ion channels and receptor signaling pathways that define the biophysical status of the sensory hair cells, contributing to hair cell development and subsequently defining the operational condition of the hair cells across the broad dynamic range of physiological function.

Original languageEnglish (US)
Pages (from-to)89-118
Number of pages30
JournalJournal of Membrane Biology
Issue number2-3
StatePublished - Jan 2006


  • Acetylcholine
  • BK channel
  • Calcium channels
  • Cochlea
  • Dopamine
  • Efferent
  • Hair cell tuning
  • Inner hair cell
  • KCa
  • KCNQ4
  • Neurotransmission
  • Noise
  • Olivocochlear bundle
  • Ontogeny
  • Outer hair cell
  • P2X receptor
  • P2Y receptor
  • Potassium channels
  • Review
  • Vestibular

ASJC Scopus subject areas

  • Biophysics
  • Physiology
  • Cell Biology


Dive into the research topics of 'Hair cells - Beyond the transducer'. Together they form a unique fingerprint.

Cite this