Abstract
Selected parameters of the haemostatic system were evaluated in 12 consecutive cases of canine Cushing's syndrome. The dogs did not exhibit evidence of thromboembolic complications. Levels of factors V and X were increased significantly (P less than 0.01) and fibrinogen concentration was increased modestly (P less than 0.05) in these dogs. Levels of factors IX and VIII:C remained in the reference range. Antithrombin III (ATIII) and plasminogen concentrations were markedly elevated (P less than 0.001). The low factor VIII:C and elevated ATIII levels in the plasma were not consistent with characteristics of a hypercoagulable state. These results demonstrated that haemostatic abnormalities which occur in canine Cushing's syndrome do not necessarily represent a state predisposed to thrombosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 228-230 |
| Number of pages | 3 |
| Journal | Research in Veterinary Science |
| Volume | 41 |
| Issue number | 2 |
| State | Published - Sep 1986 |
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ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)
Cite this
Haemostatic abnormalities in canine Cushing's syndrome. / Feldman, B. F.; Rasedee, A.; Feldman, Edward C.
In: Research in Veterinary Science, Vol. 41, No. 2, 09.1986, p. 228-230.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Haemostatic abnormalities in canine Cushing's syndrome.
AU - Feldman, B. F.
AU - Rasedee, A.
AU - Feldman, Edward C
PY - 1986/9
Y1 - 1986/9
N2 - Selected parameters of the haemostatic system were evaluated in 12 consecutive cases of canine Cushing's syndrome. The dogs did not exhibit evidence of thromboembolic complications. Levels of factors V and X were increased significantly (P less than 0.01) and fibrinogen concentration was increased modestly (P less than 0.05) in these dogs. Levels of factors IX and VIII:C remained in the reference range. Antithrombin III (ATIII) and plasminogen concentrations were markedly elevated (P less than 0.001). The low factor VIII:C and elevated ATIII levels in the plasma were not consistent with characteristics of a hypercoagulable state. These results demonstrated that haemostatic abnormalities which occur in canine Cushing's syndrome do not necessarily represent a state predisposed to thrombosis.
AB - Selected parameters of the haemostatic system were evaluated in 12 consecutive cases of canine Cushing's syndrome. The dogs did not exhibit evidence of thromboembolic complications. Levels of factors V and X were increased significantly (P less than 0.01) and fibrinogen concentration was increased modestly (P less than 0.05) in these dogs. Levels of factors IX and VIII:C remained in the reference range. Antithrombin III (ATIII) and plasminogen concentrations were markedly elevated (P less than 0.001). The low factor VIII:C and elevated ATIII levels in the plasma were not consistent with characteristics of a hypercoagulable state. These results demonstrated that haemostatic abnormalities which occur in canine Cushing's syndrome do not necessarily represent a state predisposed to thrombosis.
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UR - http://www.scopus.com/inward/citedby.url?scp=0022773542&partnerID=8YFLogxK
M3 - Article
VL - 41
SP - 228
EP - 230
JO - Research in Veterinary Science
JF - Research in Veterinary Science
SN - 0034-5288
IS - 2
ER -