Haemostatic abnormalities in canine Cushing's syndrome.

B. F. Feldman, A. Rasedee, E. C. Feldman

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22 Scopus citations


Selected parameters of the haemostatic system were evaluated in 12 consecutive cases of canine Cushing's syndrome. The dogs did not exhibit evidence of thromboembolic complications. Levels of factors V and X were increased significantly (P less than 0.01) and fibrinogen concentration was increased modestly (P less than 0.05) in these dogs. Levels of factors IX and VIII:C remained in the reference range. Antithrombin III (ATIII) and plasminogen concentrations were markedly elevated (P less than 0.001). The low factor VIII:C and elevated ATIII levels in the plasma were not consistent with characteristics of a hypercoagulable state. These results demonstrated that haemostatic abnormalities which occur in canine Cushing's syndrome do not necessarily represent a state predisposed to thrombosis.

Original languageEnglish (US)
Pages (from-to)228-230
Number of pages3
JournalResearch in Veterinary Science
Issue number2
StatePublished - Sep 1986

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)


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