Abstract
Selected parameters of the haemostatic system were evaluated in 12 consecutive cases of canine Cushing's syndrome. The dogs did not exhibit evidence of thromboembolic complications. Levels of factors V and X were increased significantly (P less than 0.01) and fibrinogen concentration was increased modestly (P less than 0.05) in these dogs. Levels of factors IX and VIII:C remained in the reference range. Antithrombin III (ATIII) and plasminogen concentrations were markedly elevated (P less than 0.001). The low factor VIII:C and elevated ATIII levels in the plasma were not consistent with characteristics of a hypercoagulable state. These results demonstrated that haemostatic abnormalities which occur in canine Cushing's syndrome do not necessarily represent a state predisposed to thrombosis.
Original language | English (US) |
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Pages (from-to) | 228-230 |
Number of pages | 3 |
Journal | Research in Veterinary Science |
Volume | 41 |
Issue number | 2 |
State | Published - Sep 1986 |
ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)