Growth, nutrition, and metabolism

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

In recent years, growth, nutrition and metabolism of HIV-infected children have received increased attention for several reasons. It has been recognized for the past decade that HIV-infected children generally do not grow as well as their uninfected counterparts, but more recent evidence suggests that this is often true even in the face of adequate virologic control. Given also that growth is a predictor of survival, there has been closer scrutiny of nutritional and metabolic factors that can contribute to poor growth. Additionally, potentially serious metabolic complications of HIV infection and/or antiretroviral therapies overlap with nutritional aspects of the infection and have prompted attention to the pathophysiology of malnutrition in these children. The current state of knowledge regarding the complex interrelationships of nutrition, HIV disease, antiretroviral therapy, and growth is reviewed in this chapter. Recommendations for nutritional monitoring and support are discussed, as are therapies for certain recognized causes of malnutrition in HIV-infected children. Briefly described are the complications and recommended treatments for fat redistribution, hyperlipidemia, insulin resistance, osteonecrosis, and mitochondrial toxicity. Finally, nutritional issues most germane to resource-poor settings are highlighted. Definitions: malnutrition, growth failure Pediatric HIV disease may lead to multiple nutritional deficiencies. Deficiencies of adequate macronutrients (protein or calories) and/or micronutrients (vitamins, minerals) to maintain optimal health status is referred to as undernutrition or, more commonly, malnutrition. Many definitions for growth failure or failure to thrive (FTT) exist.

Original languageEnglish (US)
Title of host publicationHandbook of Pediatric HIV Care, Second Edition
PublisherCambridge University Press
Pages273-308
Number of pages36
ISBN (Print)9780511544781, 0521529069, 9780521529068
DOIs
StatePublished - Jan 1 2006

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Malnutrition
HIV
Growth
Child Nutrition Disorders
Failure to Thrive
Osteonecrosis
Nutritional Support
Micronutrients
Therapeutics
Hyperlipidemias
Vitamins
Health Status
HIV Infections
Minerals
Insulin Resistance
Fats
Pediatrics
Infection
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chantry, C. J., & Moye, J. (2006). Growth, nutrition, and metabolism. In Handbook of Pediatric HIV Care, Second Edition (pp. 273-308). Cambridge University Press. https://doi.org/10.1017/CBO9780511544781.011

Growth, nutrition, and metabolism. / Chantry, Caroline J; Moye, Jack.

Handbook of Pediatric HIV Care, Second Edition. Cambridge University Press, 2006. p. 273-308.

Research output: Chapter in Book/Report/Conference proceedingChapter

Chantry, CJ & Moye, J 2006, Growth, nutrition, and metabolism. in Handbook of Pediatric HIV Care, Second Edition. Cambridge University Press, pp. 273-308. https://doi.org/10.1017/CBO9780511544781.011
Chantry CJ, Moye J. Growth, nutrition, and metabolism. In Handbook of Pediatric HIV Care, Second Edition. Cambridge University Press. 2006. p. 273-308 https://doi.org/10.1017/CBO9780511544781.011
Chantry, Caroline J ; Moye, Jack. / Growth, nutrition, and metabolism. Handbook of Pediatric HIV Care, Second Edition. Cambridge University Press, 2006. pp. 273-308
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