Growth in children with acute lymphoblastic leukemia during treatment

Laura Collins, Lee Ann Zarzabal, Trishana Nayiager, Bradley H Pollock, Ronald D. Barr

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Obesity is increasingly prevalent in affluent societies and portends considerable morbidity. This is especially true in children with acute lymphoblastic leukemia (ALL) in whom the metabolic syndrome may begin during therapy, demanding clarification of the trajectory of weight gain so that effective interventions may be developed. In this retrospective study of body mass index from a single institution over a 20-year period, almost 15% of children with ALL were at risk of overweight or frankly overweight (body mass index >85th centile) at diagnosis. This proportion increased steadily, reaching 40% at the end of treatment. Strategies to limit weight gain will have to be instituted early in the management of children with ALL, and will probably have to be maintained throughout and after the completion of active treatment.

Original languageEnglish (US)
JournalJournal of Pediatric Hematology/Oncology
Volume32
Issue number8
DOIs
StatePublished - Nov 2010
Externally publishedYes

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Precursor Cell Lymphoblastic Leukemia-Lymphoma
Weight Gain
Body Mass Index
Growth
Therapeutics
Retrospective Studies
Obesity
Morbidity

Keywords

  • children
  • growth
  • leukemia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology
  • Medicine(all)

Cite this

Growth in children with acute lymphoblastic leukemia during treatment. / Collins, Laura; Zarzabal, Lee Ann; Nayiager, Trishana; Pollock, Bradley H; Barr, Ronald D.

In: Journal of Pediatric Hematology/Oncology, Vol. 32, No. 8, 11.2010.

Research output: Contribution to journalArticle

Collins, Laura ; Zarzabal, Lee Ann ; Nayiager, Trishana ; Pollock, Bradley H ; Barr, Ronald D. / Growth in children with acute lymphoblastic leukemia during treatment. In: Journal of Pediatric Hematology/Oncology. 2010 ; Vol. 32, No. 8.
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